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Andreas Kuhn

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Articles 152
Citations 2022
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Recent Articles
1.
Kauffman P, He H, Kuhn A, Dalbey R
J Mol Biol . 2025 Mar; :169074. PMID: 40058572
A fundamental problem in biology is understanding how membrane proteins are inserted and assembled into their three-dimensional structures. The YidC/Oxa1/Alb3 family of proteins, found in bacteria, mitochondria, and chloroplasts plays...
2.
Kuhn A, Kruger T, Schuttler M, Engstler M, Fischer S
J R Soc Interface . 2024 Dec; 21(221):20240469. PMID: 39691086
colonies of the flagellated parasite exhibit characteristic fingering instability patterns. To enable data-driven and data-validated mechanistic modelling of these complex growth processes, it is crucial to first establish appropriate quantitative...
3.
Wenzel S, Hess R, Kiefer D, Kuhn A
Viruses . 2024 Apr; 16(4). PMID: 38675830
The molecular mechanism of how the infecting DNA of bacteriophage T4 passes from the capsid through the bacterial cell wall and enters the cytoplasm is essentially unknown. After adsorption, the...
4.
Ehmann F, Kuhn A, Pasmooij A, Humphreys A, Van Hengel A, Dooley B, et al.
Nucleic Acid Ther . 2024 Jan; 34(1):4-11. PMID: 38174996
RNA-based medicines have potential to treat a large variety of diseases, and research in the field is very dynamic. Proactively, The European Medicines Agency (EMA) organized a virtual conference on...
5.
Stewart H, Grinfeld D, Giannakopulos A, Petzoldt J, Shanley T, Garland M, et al.
Anal Chem . 2023 Oct; 95(42):15656-15664. PMID: 37815927
The growing trend toward high-throughput proteomics demands rapid liquid chromatography-mass spectrometry (LC-MS) cycles that limit the available time to gather the large numbers of MS/MS fragmentation spectra required for identification....
6.
Blaimschein N, Parameswaran H, Nagler G, Manioglu S, Helenius J, Ardelean C, et al.
Structure . 2023 Sep; 31(11):1419-1430.e5. PMID: 37708891
The insertion and folding of proteins into membranes is crucial for cell viability. Yet, the detailed contributions of insertases remain elusive. Here, we monitor how the insertase YidC guides the...
7.
Wolfien M, Ahmadi N, Fitzer K, Grummt S, Heine K, Jung I, et al.
J Med Internet Res . 2023 Jul; 25:e45948. PMID: 37486754
The vast and heterogeneous data being constantly generated in clinics can provide great wealth for patients and research alike. The quickly evolving field of medical informatics research has contributed numerous...
8.
Akazawa Y, Fujioka T, Yazaki K, Strbad M, Horer J, Kuhn A, et al.
J Am Soc Echocardiogr . 2023 Feb; 36(6):634-643. PMID: 36841267
Background: Abnormal atrioventricular and intraventricular electrical conduction and dysfunction of the functional right ventricle (fRV) are common in Ebstein anomaly (EA). However, fRV mechanical dyssynchrony and its relation to fRV...
9.
Dalbey R, Kaushik S, Kuhn A
Biochim Biophys Acta Mol Cell Res . 2022 Nov; 1870(2):119403. PMID: 36427551
The membrane insertase YidC, is an essential bacterial component and functions in the folding and insertion of many membrane proteins during their biogenesis. It is a multispanning protein in the...
10.
Reinecke I, Bathelt F, Sedlmayr M, Kuhn A
Stud Health Technol Inform . 2022 Sep; 298:73-77. PMID: 36073459
Data quality is essential for utilizing real world data (RWD) in scientific context. Based on drug prescriptions in a hospital information system (HIS), algorithms performed a mapping of unstructured drug...