Andreas Borst
Overview
Explore the profile of Andreas Borst including associated specialties, affiliations and a list of published articles.
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13
Citations
229
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Recent Articles
1.
Uresin D, Pyper D, Borst A, Hadjeras L, Gelhausen R, Backofen R, et al.
Front Microbiol
. 2023 Dec;
14:1280972.
PMID: 38094630
It is increasingly recognized that very small proteins (μ-proteins) are ubiquitously found in all species of the three domains of life, and that they fulfill important functions. The halophilic archaeon...
2.
Huber M, Vogel N, Borst A, Pfeiffer F, Karamycheva S, Wolf Y, et al.
Front Microbiol
. 2023 Nov;
14:1291523.
PMID: 38029211
Genomes of bacteria and archaea contain a much larger fraction of unidirectional (serial) gene pairs than convergent or divergent gene pairs. Many of the unidirectional gene pairs have short overlaps...
3.
Gomes-Filho J, Breuer R, Morales-Filloy H, Pozhydaieva N, Borst A, Paczia N, et al.
Nat Commun
. 2023 Nov;
14(1):7597.
PMID: 37989750
NAD is a coenzyme central to metabolism that also serves as a 5'-terminal cap for bacterial and eukaryotic transcripts. Thermal degradation of NAD can generate nicotinamide and ADP-ribose (ADPR). Here,...
4.
Schramm F, Borst A, Linne U, Soppa J
Front Microbiol
. 2021 Nov;
12:742806.
PMID: 34764944
Translation is an important step in gene expression. Initiation of translation is rate-limiting, and it is phylogenetically more diverse than elongation or termination. Bacteria contain only three initiation factors. In...
5.
Wasser D, Borst A, Hammelmann M, Ludt K, Soppa J
Front Microbiol
. 2021 Jun;
12:680854.
PMID: 34177864
Gene conversion is defined as the non-reciprocal transfer of genetic information from one site to a homologous, but not identical site of the genome. In prokaryotes, gene conversion can increase...
6.
Wolters M, Borst A, Pfeiffer F, Soppa J
FEMS Microbiol Lett
. 2019 Nov;
366(21).
PMID: 31769790
In haloarchaea, a cluster of three genes is localized directly adjacent to the major replication origin, and, hence, the encoded proteins were annotated as 'origin-associated proteins' (Oap). However, prior to...
7.
Grimm J, Hufnagel A, Wobser M, Borst A, Haferkamp S, Houben R, et al.
Oncogenesis
. 2018 Sep;
7(9):71.
PMID: 30237393
Approximately half of all melanoma patients harbour activating mutations in the serine/threonine kinase BRAF. This is the basis for one of the main treatment strategies for this tumor type, the...
8.
Borst A, Haferkamp S, Grimm J, Rosch M, Zhu G, Guo S, et al.
Cancer Lett
. 2017 Jul;
404:70-78.
PMID: 28720543
In patients with BRAF-mutated melanoma specific inhibitors of BRAF and MEK1/2 frequently induce initial tumor reduction, frequently followed by relapse. As demonstrated previously, BRAF-inhibition induces apoptosis only in a fraction...
9.
Hesbacher S, Pfitzer L, Wiedorfer K, Angermeyer S, Borst A, Haferkamp S, et al.
Oncotarget
. 2016 Apr;
7(22):32956-68.
PMID: 27121059
The pocket protein (PP) family consists of the three members RB1, p107 and p130 all possessing tumor suppressive properties. Indeed, the PPs jointly control the G1/S transition mainly by inhibiting...
10.
Hildebrand D, Lehle S, Borst A, Haferkamp S, Essmann F, Schulze-Osthoff K
Cell Cycle
. 2013 May;
12(12):1922-7.
PMID: 23673343
Due to its role in aging and antitumor defense, cellular senescence has recently attracted increasing interest. However, there is currently no single specific marker that can unequivocally detect senescent cells....