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Andreas Birbach

Explore the profile of Andreas Birbach including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 417
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Recent Articles
1.
Birbach A
PLoS One . 2013 Jan; 8(1):e53501. PMID: 23308238
Transgene expression from short promoters in transgenic animals can lead to unwanted transgene expression patterns, often as a byproduct of random integration of the expression cassette into the host genome....
2.
Birbach A, Eisenbarth D, Kozakowski N, Ladenhauf E, Schmidt-Supprian M, Schmid J
Neoplasia . 2011 Aug; 13(8):692-703. PMID: 21847361
In prostate cancers, epidemiological data suggest a link between prostate inflammation and subsequent cancer development, but proof for this concept in a tumor model is lacking. A constitutively active version...
3.
Sughra K, Birbach A, de Martin R, Schmid J
PLoS One . 2010 Sep; 5(9):e12683. PMID: 20856938
Background: I-kappa B kinase 2 (IKK2 or IKK-beta) is one of the most crucial signaling kinases for activation of NF-kappa B, a transcription factor that is important for inflammation, cell...
4.
Grabner B, Blaas L, Musteanu M, Hoffmann T, Birbach A, Eferl R, et al.
Genesis . 2010 Aug; 48(10):612-7. PMID: 20715176
Here we describe the generation of an inducible Cre transgenic line allowing conditional mutagenesis in ovarian granulosa cells. We have expressed the tamoxifen inducible CreER(T)² fusion protein from a Bacterial...
5.
Jiang M, Strand D, Fernandez S, He Y, Yi Y, Birbach A, et al.
Stem Cells . 2009 Dec; 28(2):344-56. PMID: 20020426
Tissue remodeling or regeneration is believed to initiate from multipotent stem and progenitor cells. We report here the establishment of two spontaneously immortalized adult non-tumorigenic human prostate epithelial cell lines,...
6.
Birbach A, Casanova E, Schmid J
Genesis . 2009 Oct; 47(11):757-64. PMID: 19830822
Tissue-specific transgene expression in the prostate epithelium has previously been achieved using short prostate-specific promoters, rendering transgenic mouse lines susceptible to integration site-dependent effects. Here we demonstrate the applicability of...
7.
Birbach A
Bioessays . 2008 Sep; 30(10):994-1002. PMID: 18798527
Thirty years after its initial characterization and more than 1000 publications listed in PubMed describing its properties, the small (ca 15 kDa) protein profilin continues to surprise us with new,...
8.
Schmid J, Birbach A
Cytokine Growth Factor Rev . 2008 Mar; 19(2):157-65. PMID: 18308615
IKKbeta/IKBKB (IkappaB kinase beta), also designated as IKK2, was named after its function of phosphorylating IkappaB molecules, the inhibitors of NF-kappaB transcription factors. The kinase activity of IKKbeta targets two...
9.
Schmid J, Birbach A
Thromb Haemost . 2007 Mar; 97(3):378-84. PMID: 17334504
The advent of fluorescent proteins has revolutionized signaling research, shifting focus from biochemical assays to analysis of live cells, organized tissues and even entire organisms. Modern applications of fluorescent proteins...
10.
Birbach A, Verkuyl J, Matus A
Exp Cell Res . 2006 May; 312(12):2279-87. PMID: 16716297
The actin cytoskeleton in pyramidal neurons plays a major role in activity-dependent processes underlying neuronal plasticity. The small actin-binding protein profilin shows NMDA receptor-dependent accumulation in dendritic spines, which is...