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Andrea Vergani

Explore the profile of Andrea Vergani including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 1144
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Recent Articles
1.
Wasilewska A, Murray R, Sundberg A, Uddin S, Achenbach H, Shavkin A, et al.
BMC Nephrol . 2022 Mar; 23(1):84. PMID: 35236302
Background: This study assessed the efficacy, tolerability and pharmacokinetics (PK) of lanthanum carbonate (LC) in hyperphosphatemic children and adolescents with chronic kidney disease (CKD) undergoing dialysis. Methods: This was a...
2.
Loretelli C, Rocchio F, DAddio F, Ben Nasr M, Castillo-Leon E, Dellepiane S, et al.
Metabolism . 2021 Jun; 121:154804. PMID: 34097917
Aims/hypothesis: Inflammation has a major role in diabetic kidney disease. We thus investigated the role of the IL-8-CXCR1/2 axis in favoring kidney damage in diabetes. Methods: Urinary IL-8 levels were...
3.
Usuelli V, Ben Nasr M, DAddio F, Liu K, Vergani A, El Essawy B, et al.
Am J Transplant . 2021 Mar; 21(10):3280-3295. PMID: 33764625
Despite much progress in improving graft outcome during cardiac transplantation, chronic allograft vasculopathy (CAV) remains an impediment to long-term graft survival. MicroRNAs (miRNAs) emerged as regulators of the immune response....
4.
Hutchison A, Whelton A, Thadhani R, Achenbach H, Vergani A, Wu J, et al.
Nephron . 2018 Oct; 140(4):265-274. PMID: 30352437
Background/aims: This post-marketing observational study assessed the long-term safety of lanthanum carbonate (LaC) in US patients with end-stage renal disease (NCT00567723). Methods: Patients (≥18 years old) undergoing dialysis, who had...
5.
Tezza S, Ben Nasr M, DAddio F, Vergani A, Usuelli V, Falzoni S, et al.
Diabetes . 2018 Aug; 67(10):2038-2053. PMID: 30065030
Extracellular ATP (eATP) activates T cells by engaging the P2X7R receptor. We identified two loss-of-function P2X7R mutations that are protective against type 1 diabetes (T1D) and thus hypothesized that eATP/P2X7R...
6.
DAddio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, et al.
J Clin Invest . 2018 Jul; 128(8):3490-3503. PMID: 30010623
Purinergic receptor-7 (P2X7R) signaling controls Th17 and Th1 generation/differentiation, while NOD-like receptor P3 (NLRP3) acts as a Th2 transcriptional factor. Here, we demonstrated the existence of a P2X7R/NLRP3 pathway in...
7.
DAddio F, La Rosa S, Maestroni A, Jung P, Orsenigo E, Ben Nasr M, et al.
Cell Stem Cell . 2015 Oct; 17(4):486-498. PMID: 26431183
The role of circulating factors in regulating colonic stem cells (CoSCs) and colonic epithelial homeostasis is unclear. Individuals with long-standing type 1 diabetes (T1D) frequently have intestinal symptoms, termed diabetic...
8.
Ben Nasr M, Vergani A, Avruch J, Liu L, Kefaloyianni E, DAddio F, et al.
Acta Diabetol . 2015 Mar; 52(5):917-27. PMID: 25808641
Aims: Mesenchymal stem cells (MSCs) are multipotent cells with immunomodulatory properties. We tested the ability of MSCs to delay islet allograft rejection. Methods: Mesenchymal stem cells were generated in vitro...
9.
Zandi S, Nakao S, Chun K, Fiorina P, Sun D, Arita R, et al.
Cell Rep . 2015 Feb; 10(7):1173-86. PMID: 25704819
Age is a major risk factor in age-related macular degeneration (AMD), but the underlying cause is unknown. We find increased Rho-associated kinase (ROCK) signaling and M2 characteristics in eyes of...
10.
Fotino C, Vergani A, Fiorina P, Pileggi A
Curr Med Chem . 2014 Oct; 22(7):891-901. PMID: 25312216
Diabetes is a metabolic disorder characterized by elevation of glucose levels in the blood that develops in humans as a result of genetic predisposition and environmental factors. Unbalanced glycemic control...