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Andrea Schrepper

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Articles 26
Citations 540
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Recent Articles
1.
Singerer I, Tempel L, Gruen K, Heiss J, Gutte C, Matasci M, et al.
Cardiovasc Res . 2024 Jul; 120(12):1485-1497. PMID: 39023231
Aims: Pulmonary vascular and right ventricular (RV) remodelling processes are important for development and progression of pulmonary hypertension (PH). The current study analysed the functional role of the extra domain...
2.
Tansi F, Schrepper A, Schwarzer M, Teichgraber U, Hilger I
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38891809
Pancreatic ductal adenocarcinoma (PDAC), characterized by hypovascularity, hypoxia, and desmoplastic stroma is one of the deadliest malignancies in humans, with a 5-year survival rate of only 7%. The anatomical location...
3.
Klein F, Dinesh S, Fiedler D, Grun K, Schrepper A, Bogoviku J, et al.
Int J Mol Sci . 2024 Apr; 25(7). PMID: 38612795
Growing evidence suggests the crucial involvement of inflammation in the pathogenesis of pulmonary hypertension (PH). The current study analyzed the expression of interleukin (IL)-17a and IL-22 as potential biomarkers for...
4.
Heyne E, Zeeb S, Junker C, Petzinna A, Schrepper A, Doenst T, et al.
Cells . 2024 Mar; 13(5. PMID: 38474357
Exercise capacity has been related to morbidity and mortality. It consists of an inherited and an acquired part and is dependent on mitochondrial function. We assessed skeletal muscle mitochondrial function...
5.
Heiss J, Grun K, Tempel L, Matasci M, Schrepper A, Schwarzer M, et al.
Eur J Clin Invest . 2022 Nov; 53(3):e13907. PMID: 36377348
Aims: Pulmonary hypertension (PH) is accompanied by pulmonary vascular remodelling. By targeted delivery of Interleukin-9 (IL9) via the immunocytokine F8IL9, beneficial effects could be demonstrated in a mouse model of...
6.
Schenkl C, Schrepper A, Heyne E, Doenst T, Schwarzer M
Biomedicines . 2022 Aug; 10(8). PMID: 36009569
The antitumor treatment NVP-AEW541 blocks IGF-1R. IGF-1R signaling is crucial for cardiac function, but the cardiac effects of NVP-AEW541 are ill defined. We assessed NVP-AEW541's effects on cardiac function and...
7.
Nahardani A, Leistikow S, Grun K, Kramer M, Herrmann K, Schrepper A, et al.
Diagnostics (Basel) . 2022 Jan; 12(1). PMID: 35054225
(1) Background: Pulmonary arterial hypertension (PAH) is a serious condition that is associated with many cardiopulmonary diseases. Invasive right heart catheterization (RHC) is currently the only method for the definitive...
8.
Schwarzer M, Molis A, Schenkl C, Schrepper A, Britton S, Koch L, et al.
Physiol Genomics . 2021 Jul; 53(9):395-405. PMID: 34297615
Aerobic exercise capacity is inversely related to morbidity and mortality as well as to insulin resistance. However, exercising in patients has led to conflicting results, presumably because aerobic exercise capacity...
9.
Gouyou B, Grun K, Kerschenmeyer A, Villa A, Matasci M, Schrepper A, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33801620
Background And Aims: Pulmonary hypertension (PH) is a heterogeneous disorder associated with poor prognosis. For the majority of patients, only limited therapeutic options are available. Thus, there is great interest...
10.
Heyne E, Schrepper A, Doenst T, Schenkl C, Kreuzer K, Schwarzer M
J Cell Mol Med . 2020 May; 24(12):6741-6749. PMID: 32363733
In heart failure, high-fat diet (HFD) may exert beneficial effects on cardiac mitochondria and contractility. Skeletal muscle mitochondrial dysfunction in heart failure is associated with myopathy. However, it is not...