Andrea Schrepper
Overview
Explore the profile of Andrea Schrepper including associated specialties, affiliations and a list of published articles.
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26
Citations
540
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Recent Articles
11.
Rohm I, Grun K, Muller L, Baz L, Forster M, Schrepper A, et al.
Clin Hemorheol Microcirc
. 2019 Jun;
73(4):497-522.
PMID: 31156142
Growing evidence suggests that inflammation is crucially involved in the pathogenesis of pulmonary hypertension (PH) and consecutive right heart failure. The present study analyzed the inflammatory response in lung and...
12.
Nguyen T, Schwarzer M, Schrepper A, Amorim P, Blum D, Hain C, et al.
J Am Heart Assoc
. 2018 Jun;
7(13).
PMID: 29929988
Background: Insulin resistance in diabetes mellitus has been associated with mitochondrial dysfunction. Defects at the level of mitochondria are also characteristic of heart failure. We assessed changes in cardiac insulin...
13.
Chung H, Kollmey A, Schrepper A, Kohl M, Blass M, Stehr S, et al.
Int J Mol Sci
. 2017 Apr;
18(4).
PMID: 28420138
Cardiac dysfunction, in particular of the left ventricle, is a common and early event in sepsis, and is strongly associated with an increase in patients' mortality. Acid sphingomyelinase (SMPD1)-the principal...
14.
Mayer S, Gilsbach R, Preissl S, Monroy Ordonez E, Schnick T, Beetz N, et al.
Circ Res
. 2015 Jul;
117(7):622-33.
PMID: 26195221
Rationale: In chronic heart failure, increased adrenergic activation contributes to structural remodeling and altered gene expression. Although adrenergic signaling alters histone modifications, it is unknown, whether it also affects other...
15.
Koentges C, Konig A, Pfeil K, Holscher M, Schnick T, Wende A, et al.
Basic Res Cardiol
. 2015 May;
110(4):37.
PMID: 25982881
Hypoadiponectinemia is an independent predictor of cardiovascular disease, impairs mitochondrial function in skeletal muscle, and has been linked to the pathogenesis of Type 2 diabetes. In models of Type 2...
16.
Bowen T, Mangner N, Werner S, Glaser S, Kullnick Y, Schrepper A, et al.
J Appl Physiol (1985)
. 2014 Nov;
118(1):11-9.
PMID: 25359720
Heart failure induced by myocardial infarction (MI) causes diaphragm muscle weakness, with elevated oxidants implicated. We aimed to determine whether diaphragm muscle weakness is 1) early-onset post-MI (i.e., within the...
17.
Schwarzer M, Osterholt M, Lunkenbein A, Schrepper A, Amorim P, Doenst T
J Physiol
. 2014 Jun;
592(17):3767-82.
PMID: 24951621
We investigated the impact of cardiac reactive oxygen species (ROS) during the development of pressure overload-induced heart failure. We used our previously described rat model where transverse aortic constriction (TAC)...
18.
Nguyen T, Shingu Y, Schwarzer M, Schrepper A, Doenst T
PLoS One
. 2013 Dec;
8(12):e82077.
PMID: 24312628
Background: Diastolic dysfunction in heart failure with preserved ejection fraction (HFpEF) may result in pulmonary congestion and lung remodeling. We evaluated the usefulness of major diastolic echocardiographic parameters and of...
19.
Sossdorf M, Fischer J, Meyer S, Dahlke K, Wissuwa B, Seidel C, et al.
Crit Care Med
. 2013 Jul;
41(10):e246-55.
PMID: 23887230
Objectives: High physical activity levels are associated with wide-ranging health benefits, disease prevention, and longevity. In the present study, we examined the impact of regular physical exercise on the severity...
20.
Schwarzer M, Schrepper A, Amorim P, Osterholt M, Doenst T
Am J Physiol Heart Circ Physiol
. 2012 Dec;
304(4):H529-37.
PMID: 23241325
Years ago a debate arose as to whether two functionally different mitochondrial subpopulations, subsarcolemmal mitochondria (SSM) and interfibrillar mitochondria (IFM), exist in heart muscle. Nowadays potential differences are often ignored....