Andrea P de Souza
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Explore the profile of Andrea P de Souza including associated specialties, affiliations and a list of published articles.
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11
Citations
195
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Recent Articles
1.
Silva P, da Silva G, de Souza A, Cardoso C, Fonseca C, Brito P, et al.
Trials
. 2013 Nov;
14:379.
PMID: 24216069
Background: Chronic chagasic cardiomyopathy is an inflammatory disease that occurs in approximately 30% of patients infected by the protozoan Trypanosoma cruzi, and it has a profile of high morbidity and...
2.
Jelicks L, de Souza A, Araujo-Jorge T, Tanowitz H
Trends Parasitol
. 2011 Jan;
27(3):102-5.
PMID: 21212020
Chagas disease, a neglected tropical disease discovered over 100 years ago, is caused by the intracellular parasite Trypanosoma cruzi and is most frequently associated with chronic cardiomyopathy and digestive disorders....
3.
de Souza A, Jelicks L, Tanowitz H, Olivieri B, Medeiros M, Oliveira G, et al.
Mem Inst Oswaldo Cruz
. 2010 Oct;
105(6):746-51.
PMID: 20944987
Cardiac damage is a frequent manifestation of Chagas disease, which is caused by the parasite Trypanosoma cruzi. Selenium (Se) is an essential micronutrient, the deficiency of which has been implicated...
4.
Durand J, Mukherjee S, Commodari F, de Souza A, Zhao D, Machado F, et al.
Am J Trop Med Hyg
. 2009 May;
80(5):782-7.
PMID: 19407124
Trypanosoma cruzi infection results in an increase in myocardial NO and intense inflammation. NO modulates the T. cruzi-induced myocardial inflammatory reaction. NO synthase (NOS)1-, NOS2-, and NOS3-null mice were infected...
5.
Olivieri B, de Souza A, Cotta-de-Almeida V, de Castro S, Araujo-Jorge T
Exp Parasitol
. 2006 Apr;
114(3):228-34.
PMID: 16620811
Disability and mortality as consequence of Chagas disease is enormous in South America. Recently, the success of the trypanocidal treatment with benznidazole, the only available drug, has been associated with...
6.
de Souza A, Tang B, Tanowitz H, Araujo-Jorge T, Jelicks E
Parasitol Res
. 2005 Jun;
97(2):87-90.
PMID: 15986245
Chagas' disease caused by infection with Trypanosoma cruzi leads to a myocardiopathy that evolves from the acute to the chronic phase. Magnetic resonance imaging (MRI) is an important tool for...
7.
de Souza A, Tanowitz H, Chandra M, Shtutin V, Weiss L, Morris S, et al.
Parasitol Res
. 2004 Mar;
92(6):496-501.
PMID: 14999469
Chagas' disease, caused by Trypanosoma cruzi, leads to acute myocarditis and chronic cardiomyopathy. Myocardial structure and function were evaluated in T. cruzi (Brazil strain)-infected CD1 mice by histopathology, cardiac gated...
8.
Park D, Cohen A, Frank P, Razani B, Lee H, Williams T, et al.
Biochemistry
. 2003 Dec;
42(51):15124-31.
PMID: 14690422
Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane found in most cell types. Caveolin-1 is the principal protein component of caveolae membranes in nonmuscle cells. The recent development...
9.
de Souza A, de Oliveira G, Vanderpas J, de Castro S, Rivera M, Araujo-Jorge T
Parasitol Res
. 2003 Jul;
91(1):51-4.
PMID: 12884013
Chagasic patients with cardiomyopathy have low levels of selenium (Se), a fundamental trace element. We evaluated the effect of supplementing infected mice with Se (0.25-16 ppm). Supplementation with 0.25 or...
10.
de Souza A, de Oliveira G, Neve J, Vanderpas J, Pirmez C, de Castro S, et al.
Exp Parasitol
. 2003 Feb;
101(4):193-9.
PMID: 12594959
Selenium is an essential trace element and its deficiency was implicated in heart diseases. We recently showed low Se levels in chronic chagasic patients with cardiomyopathy. Herein, mice were depleted...