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Herbert B Tanowitz

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Articles 178
Citations 4943
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Recent Articles
1.
Nisimura L, Coelho L, de Melo T, Vieira P, Victorino P, Garzoni L, et al.
Front Cell Infect Microbiol . 2020 Jul; 10:255. PMID: 32626662
Chagas disease is responsible for more than 10,000 deaths per year and about 6 to 7 million infected people worldwide. In its chronic stage, patients can develop mega-colon, mega-esophagus, and...
2.
Zheng C, Quintero O, Revere E, Oey M, Espinoza F, Puius Y, et al.
Open Forum Infect Dis . 2020 Jun; 7(5):ofaa156. PMID: 32500090
Background: Chagas disease, caused by the parasite , once considered a disease confined to Mexico, Central America, and South America, is now an emerging global public health problem. An estimated...
3.
Zaki P, Domingues E, Amjad F, Narde M, Goncalves K, Viana M, et al.
Parasitol Res . 2020 Apr; 119(6):1845. PMID: 32307581
The authors regret that Philipp E Scherer's name was spelt incorrectly in the author list. The name of the author is now corrected above.
4.
Zaki P, Domingues E, Amjad F, Narde M, Goncalves K, Viana M, et al.
Parasitol Res . 2020 Mar; 119(6):1829-1843. PMID: 32206887
The underlying pathogenic mechanisms of cardiomyopathy in Chagas disease are still unsolved. In order to better clarify the role of fat on the evolution of cardiomyopathy, the present study employed...
5.
DOrleans-Juste P, Akide Ndunge O, Desbiens L, Tanowitz H, Desruisseaux M
Pharmacol Ther . 2018 Oct; 194:145-160. PMID: 30291906
Endothelins were discovered more than thirty years ago as potent vasoactive compounds. Beyond their well-documented cardiovascular properties, however, the contributions of the endothelin pathway have been demonstrated in several neuroinflammatory...
6.
Laskar D, Rose M, Gupta R, Tanowitz H, Haseeb M
Am J Trop Med Hyg . 2018 Sep; 99(5):1206-1210. PMID: 30203743
A 63-year-old woman who migrated from Nigeria to the United States was found to have an elevated total serum protein, anemia, and eosinophilia. Serum protein electrophoresis (SPEP) and serum protein...
7.
Lopez M, Tanowitz H, Garg N
Curr Clin Microbiol Rep . 2018 Jun; 5(1):45-54. PMID: 29868332
Purpose Of Review: is the causative agent of Chagas disease. Decades after initial infection, ~30% of individuals can develop chronic chagasic cardiomyopathy. There are several proposed mechanisms for pathogenesis of...
8.
Colas R, Ashton A, Mukherjee S, Dalli J, Akide-Ndunge O, Huang H, et al.
Infect Immun . 2018 Jan; 86(4). PMID: 29358332
is a protozoan parasite that causes Chagas disease (CD). CD is a persistent, lifelong infection affecting many organs, most notably the heart, where it may result in acute myocarditis and...
9.
Iacobas D, Iacobas S, Tanowitz H, Campos de Carvalho A, Spray D
Microbes Infect . 2017 Nov; 20(3):185-195. PMID: 29158000
We previously found that, in a mouse model of Chagas cardiomyopathy, 18% of the 9390 quantified unigenes were significantly regulated by Trypanosoma cruzi infection. However, treatment with bone marrow-derived mononuclear...
10.
Mascareno E, Gupta R, Martello L, Dhar-Mascareno M, Salciccioli L, Beckles D, et al.
Microbes Infect . 2017 Sep; 20(1):25-36. PMID: 28951318
Infection with Trypanosoma cruzi causes Chagas disease and results in myocardial inflammation and cardiomyopathy. Downregulated Hexim1 expression, as in Hexim1 mice, reduces cardiac inflammation and fibrosis following ischemic stress. We...