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Andrea Mountney

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Recent Articles
1.
Mountney A, Blaze J, Wang Z, Umali M, Flerlage W, Dougherty J, et al.
Front Neurol . 2021 Nov; 12:745330. PMID: 34777213
Traumatic brain injury (TBI) affects millions of Americans each year, with extremely high prevalence in the Veteran community, and sleep disturbance is one of the most commonly reported symptoms. Reduction...
2.
Sanjakdar S, Flerlage W, Kang H, Napier D, Dougherty J, Mountney A, et al.
Mil Med . 2019 Mar; 184(Suppl 1):291-300. PMID: 30901408
This study assessed the effect of caffeine on neurobehavioral recovery in the WRAIR penetrating ballistic-like brain injury (PBBI) model. Unilateral frontal PBBI was produced in the right hemisphere of anesthetized...
3.
Lu X, Cao Y, Mountney A, Liao Z, Shear D, Tortella F
J Trauma Acute Care Surg . 2017 Apr; 83(1 Suppl 1):S25-S34. PMID: 28452872
Background: Posttraumatic seizures are a medical problem affecting patients with traumatic brain injury. Yet effective treatment is lacking owing to the limitations of antiepileptic drugs (AEDs) applicable to these patients....
4.
Mountney A, Boutte A, Cartagena C, Flerlage W, Johnson W, Rho C, et al.
J Neurotrauma . 2017 Mar; 34(19):2768-2789. PMID: 28326890
Closed-head concussive injury is one of the most common causes of traumatic brain injury (TBI). Isolated concussions frequently produce acute neurological impairments, and individuals typically recover spontaneously within a short...
5.
Cartagena C, Mountney A, Hwang H, Swiercz A, Rammelkamp Z, Boutte A, et al.
PLoS One . 2016 Jul; 11(7):e0158576. PMID: 27428544
Traumatic brain injury (TBI) is an established risk factor for the development of Alzheimer's disease (AD). Here the effects of severe penetrating TBI on APP and tau cleavage processing were...
6.
Yarnell A, Barry E, Mountney A, Shear D, Tortella F, Grunberg N
Curr Protoc Neurosci . 2016 Apr; 75:9.52.1-9.52.16. PMID: 27063788
Motor and sensory deficits are common following traumatic brain injury (TBI). Although rodent models provide valuable insight into the biological and functional outcomes of TBI, the success of translational research...
7.
Caudle K, Lu X, Mountney A, Shear D, Tortella F
Restor Neurol Neurosci . 2016 Feb; 34(2):257-70. PMID: 26890099
Purpose: We assessed the therapeutic efficacy of FDA-approved anti-epileptic drug Levetiracetam (LEV) to reduce post-traumatic nonconvulsive seizure (NCS) activity and promote neurobehavioral recovery following 10% frontal penetrating ballistic-like brain injury...
8.
Kochanek P, Bramlett H, Shear D, Dixon C, Mondello S, Dietrich W, et al.
J Neurotrauma . 2015 Dec; 33(6):606-14. PMID: 26671284
Operation Brain Trauma Therapy (OBTT) is a fully operational, rigorous, and productive multicenter, pre-clinical drug and circulating biomarker screening consortium for the field of traumatic brain injury (TBI). In this...
9.
Mountney A, Boutte A, Gilsdorf J, Lu X, Tortella F, Shear D
J Neurotrauma . 2015 Nov; 33(16):1492-500. PMID: 26542887
Simvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor commonly used to reduce serum cholesterol. The beneficial effects of oral simvastatin have been reported in pre-clinical models of traumatic brain injury...
10.
Mountney A, Bramlett H, Dixon C, Mondello S, Dietrich W, Wang K, et al.
J Neurotrauma . 2015 Nov; 33(6):567-80. PMID: 26541177
Simvastatin, the fourth drug selected for testing by Operation Brain Trauma Therapy (OBTT), is a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor used clinically to reduce serum cholesterol. In addition, simvastatin has...