Andrea McEwan
Overview
Explore the profile of Andrea McEwan including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
1076
Followers
0
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Related Specialties
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Recent Articles
1.
Olivieri M, Cho T, Alvarez-Quilon A, Li K, Schellenberg M, Zimmermann M, et al.
Cell
. 2020 Jul;
182(2):481-496.e21.
PMID: 32649862
The response to DNA damage is critical for cellular homeostasis, tumor suppression, immunity, and gametogenesis. In order to provide an unbiased and global view of the DNA damage response in...
2.
Hustedt N, Alvarez-Quilon A, McEwan A, Yuan J, Cho T, Koob L, et al.
Open Biol
. 2019 Sep;
9(9):190156.
PMID: 31506018
The response to DNA replication stress in eukaryotes is under the control of the ataxia-telangiectasia and Rad3-related (ATR) kinase. ATR responds to single-stranded (ss) DNA to stabilize distressed DNA replication...
3.
Hustedt N, Saito Y, Zimmermann M, Alvarez-Quilon A, Setiaputra D, Adam S, et al.
Genes Dev
. 2019 Aug;
33(19-20):1397-1415.
PMID: 31467087
DNA repair by homologous recombination (HR) is essential for genomic integrity, tumor suppression, and the formation of gametes. HR uses DNA synthesis to repair lesions such as DNA double-strand breaks...
4.
Noordermeer S, Adam S, Setiaputra D, Barazas M, Pettitt S, Ling A, et al.
Nature
. 2018 Jul;
560(7716):117-121.
PMID: 30022168
53BP1 is a chromatin-binding protein that regulates the repair of DNA double-strand breaks by suppressing the nucleolytic resection of DNA termini. This function of 53BP1 requires interactions with PTIP and...
5.
Zimmermann M, Murina O, Reijns M, Agathanggelou A, Challis R, Tarnauskaite Z, et al.
Nature
. 2018 Jul;
559(7713):285-289.
PMID: 29973717
The observation that BRCA1- and BRCA2-deficient cells are sensitive to inhibitors of poly(ADP-ribose) polymerase (PARP) has spurred the development of cancer therapies that use these inhibitors to target deficiencies in...
6.
Wilson M, Benlekbir S, Fradet-Turcotte A, Sherker A, Julien J, McEwan A, et al.
Nature
. 2016 Jul;
536(7614):100-3.
PMID: 27462807
DNA double-strand breaks (DSBs) elicit a histone modification cascade that controls DNA repair. This pathway involves the sequential ubiquitination of histones H1 and H2A by the E3 ubiquitin ligases RNF8...
7.
Li C, Timbers T, Rose J, Bozorgmehr T, McEwan A, Rankin C
Learn Mem
. 2013 Jan;
20(2):103-8.
PMID: 23325727
Lasting memories are likely to result from a lasting change in neurotransmission. In the nematode Caenorhabditis elegans, spaced training with a tap stimulus induces habituation to the tap that lasts...
8.
Sanchez-Alvarez L, Visanuvimol J, McEwan A, Su A, Imai J, Colavita A
PLoS Genet
. 2011 Sep;
7(9):e1002257.
PMID: 21912529
Neuritogenesis is a critical early step in the development and maturation of neurons and neuronal circuits. While extracellular directional cues are known to specify the site and orientation of nascent...