Andrea Martello
Overview
Explore the profile of Andrea Martello including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
335
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0
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Recent Articles
1.
Palladino E, Bernas T, Green C, Weigel C, Singh S, Senkal C, et al.
Proc Natl Acad Sci U S A
. 2022 Sep;
119(39):e2204396119.
PMID: 36122218
Membrane contact sites (MCS), close membrane apposition between organelles, are platforms for interorganellar transfer of lipids including cholesterol, regulation of lipid homeostasis, and co-ordination of endocytic trafficking. Sphingosine kinases (SphKs),...
2.
Wong L, Martello A, Eden E
J Cell Biol
. 2021 Dec;
221(1).
PMID: 34928309
Heterogeneity in endosomal membrane phospholipid content is emerging as a regulator of endocytic trafficking pathways. Kawasaki et al. (2021. J. Cell. Biol.https://doi.org/10.1083/jcb.202103141) demonstrate exchange of endosomal PI4P for PS by...
3.
Schoop V, Martello A, Eden E, Hoglinger D
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Jun;
1866(9):158989.
PMID: 34118431
Cholesterol is an essential component of eukaryotic cellular membranes. Information about its subcellular localization and transport pathways inside cells are key for the understanding and treatment of cholesterol-related diseases. In...
4.
Mameli E, Martello A, Caporali A
FEBS J
. 2021 May;
289(11):2976-2991.
PMID: 33934518
Autophagy is an essential intracellular process for cellular quality control. It enables cell homeostasis through the selective degradation of harmful protein aggregates and damaged organelles. Autophagy is essential for recycling...
5.
Wong L, Edgar J, Martello A, Ferguson B, Eden E
Front Cell Dev Biol
. 2021 Apr;
9:640456.
PMID: 33816489
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the COVID-19 (coronavirus disease 2019) pandemic, is a positive strand RNA (+RNA) virus. Like other +RNA viruses, SARS-CoV-2 is dependent...
6.
Marverti G, Marraccini C, Martello A, DArca D, Pacifico S, Guerrini R, et al.
J Med Chem
. 2021 Mar;
64(6):3204-3221.
PMID: 33710891
Drug-target interaction, cellular internalization, and target engagement should be addressed to design a lead with high chances of success in further optimization stages. Accordingly, we have designed conjugates of folic...
7.
Bertesi M, Fantini S, Alecci C, Lotti R, Martello A, Parenti S, et al.
Front Med (Lausanne)
. 2021 Feb;
7:579383.
PMID: 33585499
The mRNA-destabilizing protein tristetraprolin (TTP), encoded by the gene, is known to be able to end inflammatory responses by directly targeting and destabilizing mRNAs encoding pro-inflammatory cytokines. We analyzed its...
8.
Martello A, Lauriola A, Mellis D, Parish E, Dawson J, Imrie L, et al.
EMBO Rep
. 2020 Apr;
21(7):e48192.
PMID: 32337819
Autophagy is an essential cellular quality control process that has emerged as a critical one for vascular homeostasis. Here, we show that trichoplein (TCHP) links autophagy with endothelial cell (EC)...
9.
Lauriola A, Martello A, Fantini S, Marverti G, Zanocco-Marani T, Davalli P, et al.
Cancers (Basel)
. 2020 Apr;
12(4).
PMID: 32316593
Mitotic perturbations frequently lead to chromosome mis-segregation that generates genome instability, thereby triggering tumor onset and/or progression. Error-free mitosis depends on fidelity-monitoring systems that ensure the temporal and spatial coordination...
10.
Martello A, Platt F, Eden E
Traffic
. 2020 Mar;
21(5):354-363.
PMID: 32129938
Cholesterol homeostasis is critical for cell function and human health. Cholesterol is heterogeneously distributed among cellular membranes, with the redistribution of endocytosed dietary cholesterol playing a pivotal role in the...