Andrea M Sprague-Getsy
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Explore the profile of Andrea M Sprague-Getsy including associated specialties, affiliations and a list of published articles.
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3
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3
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Recent Articles
1.
Ford A, Taft C, Sprague-Getsy A, Carlson G, Mate N, Sieburg M, et al.
Biomolecules
. 2025 Feb;
15(2).
PMID: 40001510
Ghrelin is a 28 amino acid peptide hormone that impacts a wide range of biological processes, including appetite regulation, glucose metabolism, growth hormone regulation, and cognitive function. To bind and...
2.
Auger S, Pedersen J, Maity S, Sprague-Getsy A, Lorimer E, Koehn O, et al.
Biochemistry
. 2024 Dec;
64(1):138-155.
PMID: 39652878
Prenylation consists of the modification of proteins with either farnesyl diphosphate (FPP) or geranylgeranyl diphosphate (GGPP) at a cysteine near the C-terminus of target proteins to generate thioether-linked lipidated proteins....
3.
Schey G, Hildebrandt E, Wang Y, Diwan S, Passetti H, Potts G, et al.
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791363
Protein farnesylation is a post-translational modification where a 15-carbon farnesyl isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase). This process often causes proteins to associate...
4.
Justyna K, Das R, Lorimer E, Hu J, Pedersen J, Sprague-Getsy A, et al.
Org Lett
. 2023 Sep;
25(36):6767-6772.
PMID: 37669435
Prenylated proteins contain C or C isoprenoids linked to cysteine residues positioned near their C-termini. Here we describe the preparation of isoprenoid diphosphate analogues incorporating diazirine groups that can be...