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Andrea J OConnor

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Articles 64
Citations 835
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Recent Articles
11.
Huang T, Li X, Maier M, OBrien-Simpson N, Heath D, OConnor A
Acta Biomater . 2023 Jan; 158:56-79. PMID: 36640952
Fungal infections pose a serious threat to human health and livelihoods. The number and variety of clinically approved antifungal drugs is very limited, and the emergence and rapid spread of...
12.
Somszor K, Bas O, Karimi F, Shabab T, Saidy N, OConnor A, et al.
ACS Macro Lett . 2022 Jun; 9(12):1732-1739. PMID: 35653675
Biodegradable coronary artery stents are sought-after alternatives to permanent stents. These devices are designed to degrade after the blood vessel heals, leaving behind a regenerated artery. The original generation of...
13.
Yang M, OConnor A, Kalionis B, Heath D
Front Med Technol . 2022 Apr; 4:834123. PMID: 35368802
Decellularized extracellular matrix (dECM) deposited by mesenchymal stromal cells (MSCs) has emerged as a promising substrate for improved expansion of MSCs. To date, essentially all studies that have produced dECM...
14.
Trengove A, Duchi S, Onofrillo C, OConnell C, Di Bella C, OConnor A
Front Med Technol . 2022 Jan; 3:773673. PMID: 35047967
Current surgical techniques to treat articular cartilage defects fail to produce a satisfactory long-term repair of the tissue. Regenerative approaches show promise in their ability to generate hyaline cartilage using...
15.
Costello D, Huntington I, Burke G, Farrugia B, OConnor A, Costello A, et al.
J Robot Surg . 2021 Sep; 16(4):749-763. PMID: 34480323
We conducted a comprehensive review of surgical simulation models used in robotic surgery education. We present an assessment of the validity and cost-effectiveness of virtual and augmented reality simulation, animal,...
16.
Kusuma G, Yang M, Brennecke S, OConnor A, Kalionis B, Heath D
ACS Biomater Sci Eng . 2021 Jan; 4(5):1760-1769. PMID: 33445333
Decellularized extracellular matrixes (dECM) derived from mesenchymal stem cell (MSC) cultures have recently emerged as cell culture substrates that improve the proliferation, differentiation, and maintenance of MSC phenotype during ex...
17.
Gu D, Tan S, OConnor A, Qiao G
ACS Biomater Sci Eng . 2021 Jan; 4(5):1696-1707. PMID: 33445326
A multicomponent hydrogel drug-delivery platform with covalent incorporation of core-cross-linked star (CCS) polymers has been fabricated through dual cross-linking reactions. The presence of amphiphilic CCS polymers enhances the mechanical stability...
18.
Jafari J, Han X, Palmer J, Tran P, OConnor A
ACS Biomater Sci Eng . 2021 Jan; 5(5):2532-2542. PMID: 33405759
Cell constructs have been utilized as building blocks in tissue engineering to closely mimic the natural tissue and also overcome some of the limitations caused by two-dimensional cultures or using...
19.
Trengove A, Di Bella C, OConnor A
Tissue Eng Part B Rev . 2020 Dec; 28(1):114-128. PMID: 33307976
Articular cartilage defects caused by injury frequently lead to osteoarthritis, a painful and costly disease. Despite widely used surgical methods to treat articular cartilage defects and a plethora of research...
20.
Huang T, Holden J, Reynolds E, Heath D, OBrien-Simpson N, OConnor A
ACS Appl Mater Interfaces . 2020 Nov; 12(50):55696-55709. PMID: 33249831
Antibiotic-resistant bacteria are a severe threat to human health. The World Health Organization's Global Antimicrobial Surveillance System has revealed widespread occurrence of antibiotic resistance among half a million patients across...