Andrea Hevener
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Explore the profile of Andrea Hevener including associated specialties, affiliations and a list of published articles.
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11
Citations
1202
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Recent Articles
1.
Zhou M, Tamburini I, Van C, Molendijk J, Nguyen C, Chang I, et al.
bioRxiv
. 2023 May;
PMID: 37214953
No abstract available.
2.
Kramerova I, Ermolova N, Eskin A, Hevener A, Quehenberger O, Armando A, et al.
Hum Mol Genet
. 2016 Mar;
25(11):2194-2207.
PMID: 27005420
Limb girdle muscular dystrophy 2A is due to loss-of-function mutations in the Calpain 3 (CAPN3) gene. Our previous data suggest that CAPN3 helps to maintain the integrity of the triad...
3.
Gombos I, Crul T, Piotto S, Gungor B, Torok Z, Balogh G, et al.
PLoS One
. 2011 Dec;
6(12):e28818.
PMID: 22174906
Aging and pathophysiological conditions are linked to membrane changes which modulate membrane-controlled molecular switches, causing dysregulated heat shock protein (HSP) expression. HSP co-inducer hydroxylamines such as BGP-15 provide advanced therapeutic...
4.
Villanueva C, Waki H, Godio C, Nielsen R, Chou W, Vargas L, et al.
Cell Metab
. 2011 Apr;
13(4):413-427.
PMID: 21459326
PPARγ and Wnt signaling are central positive and negative regulators of adipogenesis, respectively. Here we identify the groucho family member TLE3 as a transcriptional integrator of the PPARγ and Wnt...
5.
Chung J, Nguyen A, Henstridge D, Holmes A, Chan M, Mesa J, et al.
Proc Natl Acad Sci U S A
. 2008 Jan;
105(5):1739-44.
PMID: 18223156
Patients with type 2 diabetes have reduced gene expression of heat shock protein (HSP) 72, which correlates with reduced insulin sensitivity. Heat therapy, which activates HSP72, improves clinical parameters in...
6.
Lee C, Olson P, Hevener A, Mehl I, Chong L, Olefsky J, et al.
Proc Natl Acad Sci U S A
. 2006 Feb;
103(9):3444-9.
PMID: 16492734
The metabolic syndrome is a collection of obesity-related disorders. The peroxisome proliferator-activated receptors (PPARs) regulate transcription in response to fatty acids and, as such, are potential therapeutic targets for these...
7.
Watt M, Hevener A, Lancaster G, Febbraio M
Endocrinology
. 2006 Jan;
147(5):2077-85.
PMID: 16396984
Ciliary neurotrophic factor (CNTF) is a member of the gp130 receptor cytokine family recently identified as an antiobesity agent in rodents and humans by mechanisms that remain unclear. We investigated...
8.
Wiedmer T, Zhao J, Li L, Zhou Q, Hevener A, Olefsky J, et al.
Proc Natl Acad Sci U S A
. 2004 Aug;
101(36):13296-301.
PMID: 15328404
The phospholipid scramblases (PLSCR1 to PLSCR4) are a structurally and functionally unique class of proteins, which are products of a tetrad of genes conserved from Caenorhabditis elegans to humans. The...
9.
He W, Barak Y, Hevener A, Olson P, Liao D, Le J, et al.
Proc Natl Acad Sci U S A
. 2003 Dec;
100(26):15712-7.
PMID: 14660788
Syndrome X, typified by obesity, insulin resistance (IR), dyslipidemia, and other metabolic abnormalities, is responsive to antidiabetic thiazolidinediones (TZDs). Peroxisome proliferator-activated receptor (PPAR) gamma, a target of TZDs, is expressed...
10.
Wilkes J, Hevener A, Olefsky J
Diabetes
. 2003 Jul;
52(8):1904-9.
PMID: 12882904
We determined whether chronic endothelin-1 (ET-1) treatment could lead to in vivo insulin resistance. Like insulin, ET-1 acutely stimulated glucose transport in isolated soleus muscle strips of WKY rats. ET-1...