Andrea E Knowlton
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Explore the profile of Andrea E Knowlton including associated specialties, affiliations and a list of published articles.
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10
Citations
208
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Recent Articles
1.
Pham K, Delitto D, Knowlton A, Hartlage E, Madhavan R, Gonzalo D, et al.
Am J Pathol
. 2016 Apr;
186(6):1537-46.
PMID: 27102771
Commercially available, highly passaged pancreatic cancer (PC) cell lines are of limited translational value. Attempts to overcome this limitation have primarily consisted of cancer cell isolation and culture directly from...
2.
Delitto D, Zhang D, Han S, Black B, Knowlton A, Vlada A, et al.
Clin Cancer Res
. 2015 Dec;
22(7):1787-99.
PMID: 26667487
Purpose: The relationship between smoking and pancreatic cancer biology, particularly in the context of the heterogeneous microenvironment, remains incompletely defined. We hypothesized that nicotine exposure would lead to the augmentation...
3.
Delitto D, Black B, Sorenson H, Knowlton A, Thomas R, Sarosi G, et al.
BMC Cancer
. 2015 Oct;
15:783.
PMID: 26498838
Background: The tumor microenvironment impacts pancreatic cancer (PC) development, progression and metastasis. How intratumoral inflammatory mediators modulate this biology remains poorly understood. We hypothesized that the inflammatory milieu within the...
4.
Delitto D, Perez C, Han S, Gonzalo D, Pham K, Knowlton A, et al.
Cancer Immunol Immunother
. 2015 Oct;
64(12):1553-63.
PMID: 26423423
The cancer microenvironment allows tumor cells to evade immune surveillance through a variety of mechanisms. While interferon-γ (IFNγ) is central to effective antitumor immunity, its effects on the microenvironment are...
5.
Brown H, Knowlton A, Snavely E, Nguyen B, Richards T, Grieshaber S
PLoS One
. 2014 Jun;
9(6):e100763.
PMID: 24955832
Chlamydia trachomatis is an obligate intracellular bacterial pathogen and the second leading cause of sexually transmitted infections in the US. Infections cause significant morbidity and can lead to serious reproductive...
6.
Richards T, Knowlton A, Grieshaber S
BMC Microbiol
. 2013 Aug;
13:185.
PMID: 23919807
Background: The developmental cycle of the obligate intracellular pathogen Chlamydia is dependant on the formation of a unique intracellular niche termed the chlamydial inclusion. The inclusion is a membrane bound...
7.
Knowlton A, Fowler L, Patel R, Wallet S, Grieshaber S
PLoS One
. 2013 Jan;
8(1):e54022.
PMID: 23308295
Chlamydia are gram negative, obligate intracellular bacterial organisms with different species causing a multitude of infections in both humans and animals. Chlamydia trachomatis is the causative agent of the sexually...
8.
Brown H, Knowlton A, Grieshaber S
Cell Microbiol
. 2012 Jun;
14(10):1554-67.
PMID: 22646503
Chlamydia trachomatis is an obligate intracellular bacteria and the infectious agent responsible for the sexually transmitted disease Chlamydia. Infection with Chlamydia can lead to serious health sequelae such as pelvic...
9.
Knowlton A, Brown H, Richards T, Andreolas L, Patel R, Grieshaber S
Traffic
. 2011 Apr;
12(7):854-66.
PMID: 21477082
Chlamydiae are Gram negative, obligate intracellular bacteria, and Chlamydia trachomatis is the etiologic agent of the most commonly reported sexually transmitted disease in the United States. Chlamydiae undergo a biphasic...
10.
Watchman C, Bourke V, Lyon J, Knowlton A, Butler S, Grier D, et al.
J Nucl Med
. 2007 Apr;
48(4):645-54.
PMID: 17401104
Unlabelled: Current bone marrow dosimetry methods inherently assume that the target cells of interest for the assessment of leukemia risk (stochastic effects) or marrow toxicity (deterministic effects) are uniformly localized...