Anand S Merchant
Overview
Explore the profile of Anand S Merchant including associated specialties, affiliations and a list of published articles.
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13
Citations
797
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Recent Articles
1.
So J, Skrypek N, Yang H, Merchant A, Nelson G, Chen W, et al.
Cancer Res
. 2020 Apr;
80(12):2612-2627.
PMID: 32265226
Current cancer treatments are largely based on the genetic characterization of primary tumors and are ineffective for metastatic disease. Here we report that DNA methyltransferase 3B (DNMT3B) is induced at...
2.
Castro N, Rangel M, Merchant A, MacKinnon G, Cuttitta F, Salomon D, et al.
Cancer Prev Res (Phila)
. 2019 Jan;
12(3):147-158.
PMID: 30679159
Triple-negative breast cancer (TNBC) represents the poorest prognosis among all of breast cancer subtypes with no currently available effective therapy. In this study, we hypothesized that sulforaphane, a dietary component...
3.
Hollander M, Latour L, Yang D, Ishii H, Xiao Z, Min Y, et al.
Circ Res
. 2017 Oct;
121(12):1360-1369.
PMID: 29051340
Rationale: Cryptogenic strokes, those of unknown cause, have been estimated as high as 30% to 40% of strokes. Inflammation has been suggested as a critical etiologic factor. However, there is...
4.
Patel S, Sanjana N, Kishton R, Eidizadeh A, Vodnala S, Cam M, et al.
Nature
. 2017 Aug;
548(7669):537-542.
PMID: 28783722
Somatic gene mutations can alter the vulnerability of cancer cells to T-cell-based immunotherapies. Here we perturbed genes in human melanoma cells to mimic loss-of-function mutations involved in resistance to these...
5.
Bae H, Leung P, Tsuneyama K, Valencia J, Hodge D, Kim S, et al.
Hepatology
. 2016 May;
64(4):1189-201.
PMID: 27178326
Unlabelled: In most autoimmune diseases the serologic hallmarks of disease precede clinical pathology by years. Therefore, the use of animal models in defining early disease events becomes critical. We took...
6.
Castro N, Merchant A, Saylor K, Anver M, Salomon D, Golubeva Y
PLoS One
. 2016 Apr;
11(4):e0153270.
PMID: 27077656
Laser capture microdissection (LCM) of tissue is an established tool in medical research for collection of distinguished cell populations under direct microscopic visualization for molecular analysis. LCM samples have been...
7.
Dine J, OSullivan C, Voeller D, Greer Y, Chavez K, Conway C, et al.
Breast Cancer Res Treat
. 2016 Jan;
155(2):235-51.
PMID: 26759246
Previously, we found that GST-tagged tumor necrosis factor-related apoptosis inducing ligand preferentially killed triple-negative breast cancer (TNBC) cells with a mesenchymal phenotype by activating death receptor 5 (DR5). The purpose...
8.
Castro N, Fedorova-Abrams N, Merchant A, Rangel M, Nagaoka T, Karasawa H, et al.
Oncotarget
. 2015 Jun;
6(14):11910-29.
PMID: 26059540
Triple-negative breast cancer (TNBC) presents the poorest prognosis among the breast cancer subtypes and no current standard therapy. Here, we performed an in-depth molecular analysis of a mouse model that...
9.
Marino N, Collins J, Shen C, Caplen N, Merchant A, Gokmen-Polar Y, et al.
Clin Exp Metastasis
. 2014 Aug;
31(7):771-86.
PMID: 25086928
Metastasis suppressor genes (MSGs) have contributed to an understanding of regulatory pathways unique to the lethal metastatic process. When re-expressed in experimental models, MSGs block cancer spread to, and colonization...
10.
Kales S, Nau M, Merchant A, Lipkowitz S
PLoS One
. 2014 Jan;
9(1):e87116.
PMID: 24466333
The Cbl proteins (Cbl, Cbl-b, and Cbl-c) are a highly conserved family of RING finger ubiquitin ligases (E3s) that function as negative regulators of tyrosine kinases in a wide variety...