Anamika Dayal
Overview
Explore the profile of Anamika Dayal including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
216
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Recent Articles
1.
McClenaghan C, Mukadam M, Roeglin J, Tryon R, Grabner M, Dayal A, et al.
EMBO Mol Med
. 2023 May;
15(6):e16883.
PMID: 37154692
ABCC9-related intellectual disability and myopathy syndrome (AIMS) arises from loss-of-function (LoF) mutations in the ABCC9 gene, which encodes the SUR2 subunit of ATP-sensitive potassium (K ) channels. K channels are...
2.
Dayal A, Perni S, Franzini-Armstrong C, Beam K, Grabner M
Proc Natl Acad Sci U S A
. 2022 May;
119(19):e2201136119.
PMID: 35507876
The skeletal muscle dihydropyridine receptor (DHPR) β1a subunit is indispensable for full trafficking of DHPRs into triadic junctions (i.e., the close apposition of transverse tubules and sarcoplasmic reticulum [SR]), facilitation...
3.
Dayal A, Fernandez-Quintero M, Liedl K, Grabner M
Elife
. 2021 Jun;
10.
PMID: 34061024
Skeletal muscle excitation-contraction (EC) coupling roots in Ca-influx-independent inter-channel signaling between the sarcolemmal dihydropyridine receptor (DHPR) and the ryanodine receptor (RyR1) in the sarcoplasmic reticulum. Although DHPR Ca influx is...
4.
Myers J, Denman K, Dupont C, Hawash A, Novak K, Koesters A, et al.
Elife
. 2021 Apr;
10.
PMID: 33904400
In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed...
5.
Idoux R, Fuster C, Jacquemond V, Dayal A, Grabner M, Charnet P, et al.
Cell Calcium
. 2020 Sep;
91:102256.
PMID: 32866694
In response to excitation of skeletal muscle fibers, trains of action potentials induce changes in the configuration of the dihydropyridine receptor (DHPR) anchored in the tubular membrane which opens the...
6.
Dayal A, Ng S, Grabner M
Nat Commun
. 2019 Jan;
10(1):115.
PMID: 30631052
The Ca-activated Cl channel (CaCC) TMEM16A/Anoctamin 1 (ANO1) is expressed in gastrointestinal epithelia and smooth muscle cells where it mediates secretion and intestinal motility. However, ANO1 Cl conductance has never...
7.
Kaplan M, Sultana N, Benedetti A, Obermair G, Linde N, Papadopoulos S, et al.
Cell Rep
. 2018 Jun;
23(13):3891-3904.
PMID: 29949772
Formation of synapses between motor neurons and muscles is initiated by clustering of acetylcholine receptors (AChRs) in the center of muscle fibers prior to nerve arrival. This AChR patterning is...
8.
Dayal A, Schrotter K, Pan Y, Fohr K, Melzer W, Grabner M
Nat Commun
. 2017 Sep;
8(1):475.
PMID: 28883413
Skeletal muscle excitation-contraction (EC) coupling is initiated by sarcolemmal depolarization, which is translated into a conformational change of the dihydropyridine receptor (DHPR), which in turn activates sarcoplasmic reticulum (SR) Ca...
9.
Schrotter K, Dayal A, Grabner M
Cell Calcium
. 2016 Oct;
61:22-31.
PMID: 27793347
The L-type Ca channel or dihydropyridine receptor (DHPR) in vertebrate skeletal muscle is responsible for sensing sarcolemmal depolarizations and transducing this signal to the sarcoplasmic Ca release channel RyR1 via...
10.
Dayal A, Bhat V, Franzini-Armstrong C, Grabner M
Proc Natl Acad Sci U S A
. 2013 Apr;
110(18):7488-93.
PMID: 23589859
The dihydropyridine receptor (DHPR) β1a subunit is crucial for enhancement of DHPR triad expression, assembly of DHPRs in tetrads, and elicitation of DHPRα1S charge movement--the three prerequisites of skeletal muscle...