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Ana Savic-Radojevic

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Articles 62
Citations 751
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Recent Articles
1.
Pantic I, Lugonja S, Jerotic D, Pljesa-Ercegovac M, Matic M, Bakovic N, et al.
Int J Mol Sci . 2025 Jan; 26(2. PMID: 39859205
Considering the mutual relationship between redox disbalance and inflammation in (HP) infection, we aimed to evaluate whether the polymorphisms in antioxidant glutathione transferases genes ( rs1695, rs1138272, rs4925 and rs156697)...
2.
Simic P, Coric V, Pljesa I, Savic-Radojevic A, Zecevic N, Kocic J, et al.
Int J Mol Sci . 2024 May; 25(9). PMID: 38732205
The tumor microenvironment is affected by reactive oxygen species and has been suggested to have an important role in ovarian cancer (OC) tumorigenesis. The role of glutathione transferases (GSTs) in...
3.
Markovic M, Ranin J, Bukumiric Z, Jerotic D, Savic-Radojevic A, Pljesa-Ercegovac M, et al.
Int J Mol Sci . 2023 Nov; 24(22). PMID: 38003341
In SARS-CoV-2 infection, excessive activation of the immune system intensively increases reactive oxygen species levels, causing harmful hyperinflammatory and oxidative state cumulative effects which may contribute to COVID-19 severity. Therefore,...
4.
Petrovic M, Simic T, Djukic T, Radic T, Savic-Radojevic A, Zekovic M, et al.
Life (Basel) . 2023 Jun; 13(6). PMID: 37374052
Members of the omega class of glutathione transferases (GSTs), GSTO1, and GSTO2, catalyze a range of reduction reactions as a part of the antioxidant defense system. Polymorphisms of genes encoding...
5.
Asanin M, Ercegovac M, Krljanac G, Djukic T, Coric V, Jerotic D, et al.
Int J Mol Sci . 2023 Jun; 24(12). PMID: 37373377
Although disturbance of redox homeostasis might be responsible for COVID-19 cardiac complications, this molecular mechanism has not been addressed yet. We have proposed modifying the effects of antioxidant proteins polymorphisms...
6.
Pavlovic D, Ristic S, Djukanovic L, Matic M, Kovacevic M, Pljesa-Ercegovac M, et al.
Medicina (Kaunas) . 2023 Jan; 59(1). PMID: 36676788
Background and Objectives: In the development of type 2 diabetes mellitus (T2DM) and its complications, genetic and environmental factors play important roles. Diabetic nephropathy (DN), one of the major microangiopathic...
7.
Simic P, Pljesa I, Nejkovic L, Jerotic D, Coric V, Stulic J, et al.
Medicina (Kaunas) . 2022 Nov; 58(11). PMID: 36422199
Chemotherapy resistance of ovarian cancer, regarded as the most lethal malignant gynecological disease, can be explained by several mechanisms, including increased activity of efflux transporters leading to decreased intracellular drug...
8.
Ercegovac M, Asanin M, Savic-Radojevic A, Ranin J, Matic M, Djukic T, et al.
Antioxidants (Basel) . 2022 May; 11(5). PMID: 35624818
Understanding the sequelae of COVID-19 is of utmost importance. Neuroinflammation and disturbed redox homeostasis are suggested as prevailing underlying mechanisms in neurological sequelae propagation in long-COVID. We aimed to investigate...
9.
Jerotic D, Ranin J, Bukumiric Z, Djukic T, Coric V, Savic-Radojevic A, et al.
Redox Rep . 2022 Apr; 27(1):85-91. PMID: 35361071
Due to the role of oxidative stress in the pathophysiology of COVID-19, it is biologically plausible that inter-individual differences in patients' clinical manifestations might be affected by antioxidant genetic profile....
10.
Djukic T, Stevanovic G, Coric V, Bukumiric Z, Pljesa-Ercegovac M, Matic M, et al.
J Pers Med . 2022 Mar; 12(3). PMID: 35330457
Based on the close relationship between dysregulation of redox homeostasis and immune response in SARS-CoV-2 infection, we proposed a possible modifying role of and glutathione transferase omega () polymorphisms in...