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Ana Isabel Loureiro

Explore the profile of Ana Isabel Loureiro including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 33
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Recent Articles
1.
Araujo F, Doria M, Beliaev A, Kiss L, Bonifacio M, Holenz J, et al.
Xenobiotica . 2024 Oct; 54(10):796-807. PMID: 39359020
The metabolism and disposition of zamicastat, a reversible dopamine β-hydroxylase (DβH) inhibitor, developed for treatment of Pulmonary Arterial Hypertension (PAH), were investigated in rats after oral and intravenous administration of...
2.
Raimundo S, Loureiro A, Vieira F, Fernandes A
Arch Bronconeumol . 2022 Apr; 56(7):465-466. PMID: 35373760
No abstract available.
3.
Pires N, Loureiro A, Igreja B, Lacroix P, Soares-da-Silva P
Eur J Pharmacol . 2015 Feb; 750:98-107. PMID: 25641747
Etamicastat, a peripheral reversible dopamine-β-hydroxylase inhibitor, blocked the hERG current amplitude with an IC50 value of 44.0µg/ml in HEK 293 cells. At 0.3 and 3µg/ml, etamicastat had no effects on...
4.
Igreja B, Pires N, Bonifacio M, Loureiro A, Fernandes-Lopes C, Wright L, et al.
Hypertens Res . 2014 Oct; 38(1):30-8. PMID: 25298210
Hyperactivation of the sympathetic nervous system has an important role in the development and progression of arterial hypertension. This study evaluated the efficacy of etamicastat, a dopamine-β-hydroxylase (DβH) inhibitor, in...
5.
Antunes A, Gomes J, Belchior I, Loureiro A, Carvalho A, Madeira A, et al.
Eur Respir J . 2012 Dec; 40(6):1581-2. PMID: 23204028
No abstract available.
6.
Palma P, Bonifacio M, Loureiro A, Soares-da-Silva P
J Comput Chem . 2012 Jan; 33(9):970-86. PMID: 22278964
Alchemical free energy simulations are amongst the most accurate techniques for the computation of the free energy changes associated with noncovalent protein-ligand interactions. A procedure is presented to estimate the...
7.
Loureiro A, Pinto C, Oliveira A, Calvario F, Carvalho A, Duarte R
Acta Med Port . 2011 Oct; 24(2):371-4. PMID: 22011613
In recent years there has been an increase in the number of cases of intestinal tuberculosis mainly due to the HIV epidemic. Its clinical manifestations and endoscopic findings are nonspecific,...