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Ana Cindric

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Recent Articles
1.
Cindric A, Vuckovic F, Murray A, Klaric T, Alic I, Kristic J, et al.
BBA Adv . 2025 Jan; 7():100137. PMID: 39845703
Down syndrome (DS), a genetic condition caused by trisomy 21 (T21), manifests various neurological symptoms, including intellectual disability, early neurodegeneration, and early-onset dementia. N-glycosylation is a protein modification that plays...
2.
Luksic F, Mijakovac A, Josipovic G, Vicic Bockor V, Kristic J, Cindric A, et al.
Biomolecules . 2023 Aug; 13(8). PMID: 37627310
Glycosylation of IgG regulates the effector function of this antibody in the immune response. Glycosylated IgG is a potent therapeutic used for both research and clinical purposes. While there is...
3.
Murray A, Gough G, Cindric A, Vuckovic F, Koschut D, Borelli V, et al.
EBioMedicine . 2023 Jul; 94:104692. PMID: 37451904
Background: People with Down syndrome (DS) show clinical signs of accelerated ageing. Causative mechanisms remain unknown and hypotheses range from the (essentially untreatable) amplified-chromosomal-instability explanation, to potential actions of individual...
4.
Birukov A, Plavsa B, Eichelmann F, Kuxhaus O, Hoshi R, Rudman N, et al.
Diabetes Care . 2022 Sep; 45(11):2729-2736. PMID: 36174116
Objective: N-glycosylation is a functional posttranslational modification of immunoglobulins (Igs). We hypothesized that specific IgG N-glycans are associated with incident type 2 diabetes and cardiovascular disease (CVD). Research Design And...
5.
Deris H, Kifer D, Cindric A, Petrovic T, Cvetko A, Trbojevic-Akmacic I, et al.
iScience . 2022 Mar; 25(3):103897. PMID: 35243255
Gonadal hormones affect immunoglobulin G (IgG) glycosylation, and the more proinflammatory IgG glycome composition might be one of the molecular mechanisms behind the increased proinflammatory phenotype in perimenopause. Using ultra-high-performance...
6.
Cindric A, Kristic J, Kavur M, Pezer M
Adv Exp Med Biol . 2021 Sep; 1325:341-373. PMID: 34495544
Human lifespan has increased significantly in the last 200 years, emphasizing our need to age healthily. Insights into molecular mechanisms of aging might allow us to slow down its rate...
7.
Kifer D, Louca P, Cvetko A, Deris H, Cindric A, Grallert H, et al.
J Hypertens . 2021 Jul; 39(12):2527-2533. PMID: 34285147
Objectives: Glycosylation of immunoglobulin G (IgG) is an important regulator of the immune system and has been implicated in prevalent hypertension. The aim of this study is to investigate whether...
8.
Deris H, Cindric A, Lauber M, Petrovic T, Bielik A, Taron C, et al.
Glycobiology . 2021 Jun; 31(9):1062-1067. PMID: 34132802
Protein glycosylation is the attachment of a carbohydrate moiety to a protein backbone affecting both structure and function of the protein. Abnormal glycosylation is associated with various diseases, and some...
9.
Greto V, Cvetko A, Stambuk T, Dempster N, Kifer D, Deris H, et al.
Int J Obes (Lond) . 2021 May; 45(7):1521-1531. PMID: 33941843
Background: Obesity, a major global health problem, is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent posttranslational modification, highly responsive to inflammation and ageing. The prospect...