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Ana C Leandro

Explore the profile of Ana C Leandro including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 48
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Recent Articles
1.
Rodrigue A, Knowles E, Mollon J, Mathias S, Peralta J, Leandro A, et al.
Hum Brain Mapp . 2025 Jan; 46(1):e70101. PMID: 39757975
Phenotypic and genetic relationships between white matter microstructure (i.e., fractional anisotropy [FA]) and peripheral inflammatory responses (i.e., circulating cytokines) have important implications for health and disease. However, it is unclear...
2.
Manusov E, Diego V, Almeida M, Ortiz D, Curran J, Galan J, et al.
Genes (Basel) . 2024 Aug; 15(8). PMID: 39202366
This study examines the complex interplay of genetic and environmental interactions that shape chronic illness risk. Evidence is mounting for the role of genetic expression and the immune response in...
3.
Aceves M, Granados J, Leandro A, Peralta J, Glahn D, Williams-Blangero S, et al.
Genes (Basel) . 2024 May; 15(5). PMID: 38790197
Currently, more than 55 million people around the world suffer from dementia, and Alzheimer's Disease and Related Dementias (ADRD) accounts for nearly 60-70% of all those cases. The spread of...
4.
Kumar S, Granados J, Aceves M, Peralta J, Leandro A, Thomas J, et al.
Cells . 2024 Mar; 13(5. PMID: 38474333
A large portion of the heterogeneity in coronavirus disease 2019 (COVID-19) susceptibility and severity of illness (SOI) remains poorly understood. Recent evidence suggests that SARS-CoV-2 infection-associated damage to alveolar epithelial...
5.
Xiong X, Samollow P, Cao W, Metz R, Zhang C, Leandro A, et al.
G3 (Bethesda) . 2021 Nov; 12(1). PMID: 34751383
The gray short-tailed opossum (Monodelphis domestica) is an established laboratory-bred marsupial model for biomedical research. It is a critical species for comparative genomics research, providing the pivotal phylogenetic outgroup for...
6.
Blackburn N, Meikle P, Peralta J, Kumar S, Leandro A, Bellinger M, et al.
Circ Genom Precis Med . 2021 Apr; 14(3):e003232. PMID: 33887960
Background: The identification and understanding of therapeutic targets for atherosclerotic cardiovascular disease is of fundamental importance given its global health and economic burden. Inhibition of ANGPTL3 (angiopoietin-like 3) has demonstrated...
7.
Kumar S, Curran J, Kumar K, DeLeon E, Leandro A, Peralta J, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33805011
The in vitro modeling of cardiac development and cardiomyopathies in human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs) provides opportunities to aid the discovery of genetic, molecular, and developmental changes...
8.
Kumar S, Curran J, DeLeon E, Leandro A, Howard T, Lehman D, et al.
Int J Mol Sci . 2020 Sep; 21(19). PMID: 32977388
miRNA regulates the expression of protein coding genes and plays a regulatory role in human development and disease. The human iPSCs and their differentiated progenies provide a unique opportunity to...
9.
Kumar S, Espinosa E, Leandro A, Curran J, Blangero J
Am J Stem Cells . 2019 Sep; 8(2):28-37. PMID: 31523484
A large number of Epstein Barr virus (EBV) immortalized lymphoblastoid cell lines (LCLs) have been generated and maintained in genetic/epidemiological studies as a perpetual source of DNA and as a...
10.
Blackburn N, Michael L, Meikle P, Peralta J, Mosior M, McAhren S, et al.
J Lipid Res . 2019 Jun; 60(9):1630-1639. PMID: 31227640
The de novo ceramide synthesis pathway is essential to human biology and health, but genetic influences remain unexplored. The core function of this pathway is the generation of biologically active...