Ana-Cristina Dragomir
Overview
Explore the profile of Ana-Cristina Dragomir including associated specialties, affiliations and a list of published articles.
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7
Citations
510
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Recent Articles
1.
Kocabayoglu P, Lade A, Lee Y, Dragomir A, Sun X, Fiel M, et al.
J Hepatol
. 2015 Feb;
63(1):141-7.
PMID: 25678385
Background & Aims: Rapid induction of β-PDGF receptor (β-PDGFR) is a core feature of hepatic stellate cell activation, but its cellular impact in vivo is not well characterized. We explored...
2.
Zheng R, Dragomir A, Mishin V, Richardson J, Heck D, Laskin D, et al.
Toxicol Appl Pharmacol
. 2014 May;
279(1):43-52.
PMID: 24832492
The lipid peroxidation end-product 4-hydroxynonenal (4-HNE) is generated in tissues during oxidative stress. As a reactive aldehyde, it forms Michael adducts with nucleophiles, a process that disrupts cellular functioning. Liver,...
3.
Jan Y, Heck D, Dragomir A, Gardner C, Laskin D, Laskin J
Chem Res Toxicol
. 2014 Mar;
27(5):882-94.
PMID: 24661219
Acetaminophen (APAP) is metabolized in the liver to N-acetyl-p-benzoquinone imine (NAPQI), an electrophilic metabolite known to bind liver proteins resulting in hepatotoxicity. Mammalian thioredoxin reductase (TrxR) is a cellular antioxidant...
4.
Jiao J, Dragomir A, Kocabayoglu P, Rahman A, Chow A, Hashimoto D, et al.
J Immunol
. 2014 Mar;
192(7):3374-82.
PMID: 24591364
Neutrophils are the most abundant cell type in the immune system and play an important role in the innate immune response. Using a diverse range of mouse models with either...
5.
Pradere J, Kluwe J, De Minicis S, Jiao J, Gwak G, Dapito D, et al.
Hepatology
. 2013 Apr;
58(4):1461-73.
PMID: 23553591
Unlabelled: Although it is well established that hepatic macrophages play a crucial role in the development of liver fibrosis, the underlying mechanisms remain largely elusive. Moreover, it is not known...
6.
Dragomir A, Sun R, Mishin V, Hall L, Laskin J, Laskin D
Toxicol Sci
. 2012 Mar;
127(2):609-19.
PMID: 22461450
Galectin-3 (Gal-3) is a β-galactoside-binding lectin implicated in the regulation of macrophage activation and inflammatory mediator production. In the present studies, we analyzed the role of Gal-3 in liver inflammation...
7.
Dragomir A, Laskin J, Laskin D
Toxicol Appl Pharmacol
. 2011 Apr;
253(3):170-7.
PMID: 21513726
Toxic doses of acetaminophen (AA) cause hepatocellular necrosis. Evidence suggests that activated macrophages contribute to the pathogenic process; however, the factors that activate these cells are unknown. In these studies,...