Amy Scarborough
Overview
Explore the profile of Amy Scarborough including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
49
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0
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Recent Articles
1.
Elgazzaz M, Lakkappa N, Berdasco C, Mohan U, Nuzzo A, Restivo L, et al.
Hypertension
. 2024 Nov;
82(1):84-95.
PMID: 39601126
Background: Ang-II (angiotensin II) impairs the function of the antihypertensive enzyme ACE2 (angiotensin-converting enzyme 2) by promoting its internalization, ubiquitination, and degradation, thus contributing to hypertension. However, few ACE2 ubiquitination...
2.
Greiffenstein P, Cavalea A, Smith A, Sharp T, Warren O, Dennis J, et al.
J Trauma Acute Care Surg
. 2024 Oct;
98(2):251-257.
PMID: 39375890
Background: Pulseless electrical activity from hemorrhagic shock has not been shown to benefit from cardiopulmonary resuscitation (CPR). Using a porcine model, our objective was to determine the effects of CPR...
3.
Elgazzaz M, Lakkappa N, Berdasco C, Mohan U, Nuzzo A, Restivo L, et al.
medRxiv
. 2024 Jun;
PMID: 38826318
Background: Angiotensin (Ang)-II impairs the function of the antihypertensive enzyme ACE2 by promoting its internalization, ubiquitination and degradation thus contributing to hypertension. However, few ACE2 ubiquitination partners have been identified...
4.
Sukhanov S, Higashi Y, Yoshida T, Danchuk S, Alfortish M, Goodchild T, et al.
JCI Insight
. 2023 Jan;
8(4).
PMID: 36602878
Although murine models of coronary atherosclerotic disease have been used extensively to determine mechanisms, limited new therapeutic options have emerged. Pigs with familial hypercholesterolemia (FH pigs) develop complex coronary atheromas...
5.
Huson H, Goodchild T, Sun L, Scarborough A, Novak T, Dubansky B, et al.
J Surg Res
. 2022 Apr;
276:354-361.
PMID: 35429684
Introduction: Gastrointestinal anastomoses are performed millions of times per year worldwide. The major complication they share is anastomotic leak. We describe the development and initial safety/efficacy of a novel luminal...
6.
Sharp 3rd T, Gong Z, Scarborough A, Goetzman E, Ali M, Spaletra P, et al.
JACC Basic Transl Sci
. 2020 Aug;
5(7):699-714.
PMID: 32760857
With the complexities that surround myocardial ischemia/reperfusion (MI/R) injury, therapies adjunctive to reperfusion that elicit beneficial pleiotropic effects and do not overlap with standard of care are necessary. This study...
7.
Polhemus D, Trivedi R, Sharp T, Li Z, Goodchild T, Scarborough A, et al.
Basic Res Cardiol
. 2019 Jan;
114(2):9.
PMID: 30656501
Enthusiasm for cell therapy for myocardial injury has waned due to equivocal benefits in clinical trials. In an attempt to improve efficacy, we investigated repeated cell therapy and adjunct renal...
8.
Trivedi R, Polhemus D, Li Z, Yoo D, Koiwaya H, Scarborough A, et al.
J Am Heart Assoc
. 2018 Mar;
7(5).
PMID: 29502102
Background: There is a paucity of data about the mechanisms by which sacubitril/valsartan (also known as LCZ696) improves outcomes in patients with heart failure. Specifically, the effects of sacubitril/valsartan on...