Amy L Hazen
Overview
Explore the profile of Amy L Hazen including associated specialties, affiliations and a list of published articles.
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10
Citations
300
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Recent Articles
1.
Korf J, Honarpisheh P, Mohan E, Banerjee A, Blasco-Conesa M, Honarpisheh P, et al.
J Immunol
. 2022 Jun;
209(2):288-300.
PMID: 35732342
Recent studies have highlighted the deleterious contributions of B cells to post-stroke recovery and cognitive decline. Different B cell subsets have been proposed on the basis of expression levels of...
2.
Honarpisheh P, Blixt F, Blasco Conesa M, Won W, dAigle J, Munshi Y, et al.
Brain Behav Immun
. 2020 Aug;
90:235-247.
PMID: 32861719
Aging is associated with dysfunction of the gut microbiota-immune-brain axis, a major regulatory axis in both brain health and in central nervous system (CNS) diseases. Antigen presenting cells (APCs) play...
3.
Al Mamun A, Chauhan A, Qi S, Ngwa C, Xu Y, Sharmeen R, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(3):1742-1752.
PMID: 31892541
Microglial activation plays a central role in poststroke inflammation and causes secondary neuronal damage; however, it also contributes in debris clearance and chronic recovery. Microglial pro- and antiinflammatory responses (or...
4.
Laskowski T, Hazen A, Collazo R, Haviland D
Cytometry A
. 2019 Aug;
97(2):116-125.
PMID: 31454153
The rapid advancement of immunotherapy strategies has created a need for technologies that can reliably and reproducibly identify rare populations, detect subtle changes in modulatory signals, and assess antigenic expression...
5.
Hazen A, Bushnell T, Haviland D
Methods
. 2018 Jan;
134-135:130-135.
PMID: 29371108
With the release and use of the Becton Dickenson FACS Diva Software, the use of Area as the default parameter came into play. As such, the use of area as...
6.
Collazo M, Paraiso K, Park M, Hazen A, Kerr W
Eur J Immunol
. 2012 Apr;
42(7):1785-95.
PMID: 22535653
We previously showed that germline or induced SHIP deficiency expands immuno-regulatory cell numbers in T lymphoid and myeloid lineages. We postulated these increases could be interrelated. Here, we show that...
7.
Hazen A, Diks S, Wahle J, Fuhler G, Peppelenbosch M, Kerr W
J Proteome Res
. 2011 Jun;
10(8):3542-50.
PMID: 21648952
The changes in signal transduction associated with the acquisition of specific cell fates remain poorly understood. We performed massive parallel assessment of kinase signatures of the radiations of the hematopoietic...
8.
Abbas H, Maccio D, Coskun S, Jackson J, Hazen A, Sills T, et al.
Cell Stem Cell
. 2010 Nov;
7(5):606-17.
PMID: 21040902
Mdm2 is an E3 ubiquitin ligase that targets p53 for degradation. p53(515C) (encoding p53R172P) is a hypomorphic allele of p53 that rescues the embryonic lethality of Mdm2(-/-) mice. Mdm2(-/-) p53(515C/515C)...
9.
Hazen A, Smith M, Desponts C, Winter O, Moser K, Kerr W
Blood
. 2008 Dec;
113(13):2924-33.
PMID: 19074735
SH2-domain-containing inositol 5'-phosphatase-1 (SHIP) deficiency significantly increases the number of hematopoietic stem cells (HSCs) present in the bone marrow (BM). However, the reconstitution capacity of these HSCs is severely impaired,...
10.
Desponts C, Hazen A, Paraiso K, Kerr W
Blood
. 2006 Feb;
107(11):4338-45.
PMID: 16467196
The SH2 domain-containing inositol 5'-phosphatase-1 (SHIP) has the potential to modulate multiple signaling pathways downstream of receptors that impact hematopoietic stem cell (HSC) biology. Therefore, we postulated that SHIP might...