Amy J C Brook
Overview
Explore the profile of Amy J C Brook including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
110
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Davis T, Brook A, Rokicki M, Bagley M, Kipling D
Pharmaceuticals (Basel)
. 2016 May;
9(2).
PMID: 27136566
Progeroid syndromes show features of accelerated ageing and are used as models for human ageing, of which Werner syndrome (WS) is one of the most widely studied. WS fibroblasts show...
2.
Alimbetov D, Davis T, Brook A, Cox L, Faragher R, Nurgozhin T, et al.
Biogerontology
. 2015 Sep;
17(2):305-15.
PMID: 26400758
Senescent cells show an altered secretome profile termed the senescence-associated secretory phenotype (SASP). There is an increasing body of evidence that suggests that the accumulation of SASP-positive senescent cells in...
3.
Davis T, Tivey H, Brook A, Kipling D
Biogerontology
. 2014 Sep;
16(1):43-51.
PMID: 25214013
Fibroblasts from the progeroid Nijmegen breakage syndrome that express a truncated version of the nibrin protein (NBN(p70)) undergo premature senescence and have an enlarged morphology with high levels of senescence-associated...
4.
Tivey H, Brook A, Rokicki M, Kipling D, Davis T
Biogerontology
. 2012 Nov;
14(1):47-62.
PMID: 23112078
Werner Syndrome (WS) is a human segmental progeria resulting from mutations in a DNA helicase. WS fibroblasts have a shortened replicative capacity, an aged appearance, and activated p38 MAPK, features...
5.
Davis T, Tivey H, Brook A, Grimstead J, Rokicki M, Kipling D
Age (Dordr)
. 2012 Sep;
35(5):1767-83.
PMID: 23001818
Rothmund-Thomson fibroblasts had replicative lifespans and growth rates within the range for normal fibroblasts; however, they show elevated levels of the stress-associated p38 MAP kinase, suggestive of stress during growth....