Amun Patel
Overview
Explore the profile of Amun Patel including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
13
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0
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Recent Articles
1.
Molina Vargas A, Sinha S, Osborn R, Arantes P, Patel A, Dewhurst S, et al.
Nucleic Acids Res
. 2023 Nov;
52(2):921-939.
PMID: 38033324
An increasingly pressing need for clinical diagnostics has required the development of novel nucleic acid-based detection technologies that are sensitive, fast, and inexpensive, and that can be deployed at point-of-care....
2.
Sinha S, Molina Vargas A, Arantes P, Patel A, OConnell M, Palermo G
Nucleic Acids Res
. 2023 Nov;
52(2):906-920.
PMID: 38033317
Cas13a is a recent addition to the CRISPR-Cas toolkit that exclusively targets RNA, which makes it a promising tool for RNA detection. It utilizes a CRISPR RNA (crRNA) to target...
3.
Molina Vargas A, Osborn R, Sinha S, Arantes P, Patel A, Dewhurst S, et al.
bioRxiv
. 2023 Aug;
PMID: 37547020
Key Points: Certain positions in the Cas13a crRNA-target-RNA duplex are particularly sensitive to mismatches.Understanding Cas13a's allosteric activation pathway allowed us to develop novel high-fidelity Cas13a variants.These Cas13a variants and crRNA...
4.
Sinha S, Molina Vargas A, Arantes P, Patel A, OConnell M, Palermo G
bioRxiv
. 2023 Aug;
PMID: 37546822
Cas13a is a recent addition to the CRISPR-Cas toolkit that exclusively targets RNA, which makes it a promising tool for RNA detection. The protein uses a CRISPR RNA (crRNA) to...