Amity L Manning
Overview
Explore the profile of Amity L Manning including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
2072
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Mercadante D, Crowley E, Manning A
J Vis Exp
. 2019 Oct;
(151).
PMID: 31589210
Live cell time-lapse imaging is an important tool in cell biology that provides insight into cellular processes that might otherwise be overlooked, misunderstood, or misinterpreted by the fixed-cell analysis. While...
12.
Lim S, Hermance N, Mudianto T, Mustaly H, Mauricio I, Vittoria M, et al.
Nat Commun
. 2019 Apr;
10(1):1547.
PMID: 30948712
The Hippo pathway maintains tissue homeostasis by negatively regulating the oncogenic transcriptional co-activators YAP and TAZ. Though functional inactivation of the Hippo pathway is common in tumors, mutations in core...
13.
Navarro-Serer B, Childers E, Hermance N, Mercadante D, Manning A
Oncotarget
. 2019 Mar;
10(17):1649-1659.
PMID: 30899434
The presence of supernumerary centrosomes is prevalent in cancer, where they promote the formation of transient multipolar mitotic spindles. Active clustering of supernumerary centrosomes enables the formation of a functional...
14.
Fathi A, Wander S, Blonquist T, Brunner A, Amrein P, Supko J, et al.
Haematologica
. 2016 Dec;
102(4):719-727.
PMID: 28034990
Aberrant expression of aurora kinase A is implicated in the genesis of various neoplasms, including acute myeloid leukemia. Alisertib, an aurora A kinase inhibitor, has demonstrated efficacy as monotherapy in...
15.
Nicolay B, Danielian P, Kottakis F, Lapek Jr J, Sanidas I, Miles W, et al.
Genes Dev
. 2015 Aug;
29(17):1875-89.
PMID: 26314710
The retinoblastoma tumor suppressor (pRb) protein associates with chromatin and regulates gene expression. Numerous studies have identified Rb-dependent RNA signatures, but the proteomic effects of Rb loss are largely unexplored....
16.
Manning A, Yazinski S, Nicolay B, Bryll A, Zou L, Dyson N
Mol Cell
. 2014 Mar;
53(6):993-1004.
PMID: 24613344
Chromosome instability (CIN), a common feature of solid tumors, promotes tumor evolution and increases drug resistance during therapy. We previously demonstrated that loss of the retinoblastoma protein (pRB) tumor suppressor...
17.
Evertts A, Manning A, Wang X, Dyson N, Garcia B, Coller H
Mol Biol Cell
. 2013 Aug;
24(19):3025-37.
PMID: 23924899
The transition between proliferation and quiescence is frequently associated with changes in gene expression, extent of chromatin compaction, and histone modifications, but whether changes in chromatin state actually regulate cell...
18.
Black J, Manning A, Van Rechem C, Kim J, Ladd B, Cho J, et al.
Cell
. 2013 Jul;
154(3):541-55.
PMID: 23871696
Acquired chromosomal instability and copy number alterations are hallmarks of cancer. Enzymes capable of promoting site-specific copy number changes have yet to be identified. Here, we demonstrate that H3K9/36me3 lysine...
19.
Manning A, Dyson N
Nat Rev Cancer
. 2012 Feb;
12(3):220-6.
PMID: 22318235
RB, a well known tumour suppressor that functions in the control of cell cycle progression and proliferation, has recently been shown to have additional functions in the maintenance of genomic...
20.
Zhang J, Benavente C, McEvoy J, Flores-Otero J, Ding L, Chen X, et al.
Nature
. 2012 Jan;
481(7381):329-34.
PMID: 22237022
Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very quickly following RB1 inactivation but the underlying mechanism...