Amina Abdul Qayum
Overview
Explore the profile of Amina Abdul Qayum including associated specialties, affiliations and a list of published articles.
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15
Citations
180
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Recent Articles
1.
Taruselli M, Abdul Qayum A, Abebayehu D, Caslin H, Dailey J, Kotha A, et al.
J Immunol
. 2024 Feb;
212(8):1277-1286.
PMID: 38381001
IL-33 is an inflammatory cytokine that promotes allergic disease by activating group 2 innate lymphoid cells, Th2 cells, and mast cells. IL-33 is increased in asthmatics, and its blockade suppresses...
2.
Cheung K, Jaganathan A, Hu Y, Xu F, Lejeune A, Sharma R, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(14):e2117112119.
PMID: 35344430
SignificanceSTAT3 (signal transducer and activator of transcription 3) is a master transcription factor that organizes cellular responses to cytokines and growth factors and is implicated in inflammatory disorders. STAT3 is...
3.
Taruselli M, Kolawole E, Abdul Qayum A, Haque T, Caslin H, Abebayehu D, et al.
Cell Immunol
. 2021 Dec;
371:104457.
PMID: 34883342
Statins are HMG-CoA reductase inhibitors prescribed for lowering cholesterol. They can also inhibit inflammatory responses by suppressing isoprenylation of small G proteins. Consistent with this, we previously found that fluvastatin...
4.
Paranjape A, Haque T, Kiwanuka K, Abdul Qayum A, Barnstein B, Finkelman F, et al.
Cell Immunol
. 2020 Aug;
356:104134.
PMID: 32862025
Mast cells, well established effectors in allergic disease, can be activated by numerous stimuli. We previously found that the Fyn-Stat5B pathway is critical for FcεRI-stimulated mast cell function. Because IgG...
5.
Kharwadkar R, Ulrich B, Abdul Qayum A, Koh B, Licona-Limon P, Flavell R, et al.
Immunohorizons
. 2020 May;
4(5):282-291.
PMID: 32439753
Generation of allelic gene reporter mice has provided a powerful tool to study gene function in vivo. In conjunction with imaging technologies, reporter mouse models facilitate studies of cell lineage...
6.
Abdul Qayum A, Koh B, Martin R, Kenworthy B, Kharwadkar R, Fu Y, et al.
J Immunol
. 2019 Jul;
203(5):1111-1121.
PMID: 31350354
IL-9 is an important mediator of allergic disease that is critical for mast cell-driven diseases. IL-9 is produced by many cell types, including T cells, basophils, and mast cells. Yet,...
7.
Caslin H, Abebayehu D, Abdul Qayum A, Haque T, Taruselli M, Paez P, et al.
J Immunol
. 2019 Jun;
203(2):453-464.
PMID: 31160535
Sepsis has a well-studied inflammatory phase, with a less-understood secondary immunosuppressive phase. Elevated blood lactate and slow lactate clearance are associated with mortality; however, regulatory roles are unknown. We hypothesized...
8.
Deak P, Kim B, Koh B, Abdul Qayum A, Kiziltepe T, Kaplan M, et al.
J Immunol
. 2019 May;
203(1):21-30.
PMID: 31101666
Drug allergies occur when hapten-like drug metabolites conjugated to serum proteins, through their interactions with specific IgE, trigger allergic reactions that can be life threatening. A molecule termed covalent heterobivalent...
9.
Deak P, Kim B, Abdul Qayum A, Shin J, Vitalpur G, Kloepfer K, et al.
Proc Natl Acad Sci U S A
. 2019 Apr;
116(18):8966-8974.
PMID: 30962381
Allergies are a result of allergen proteins cross-linking allergen-specific IgE (sIgE) on the surface of mast cells and basophils. The diversity and complexity of allergen epitopes, and high-affinity of the...
10.
Koh B, Abdul Qayum A, Srivastava R, Fu Y, Ulrich B, Janga S, et al.
Nat Commun
. 2018 Nov;
9(1):4803.
PMID: 30442929
Cytokine genes are regulated by multiple regulatory elements that confer tissue-specific and activation-dependent expression. The cis-regulatory elements of the gene encoding IL-9, a cytokine that promotes allergy, autoimmune inflammation and...