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Amin Addetia

Explore the profile of Amin Addetia including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 2134
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Recent Articles
1.
Park Y, Liu C, Lee J, Brown J, Ma C, Liu P, et al.
Cell . 2025 Feb; PMID: 39922192
DPP4 was considered a canonical receptor for merbecoviruses until the recent discovery of African bat-borne MERS-related coronaviruses using ACE2. The extent and diversity of ACE2 utilization among merbecoviruses and their...
2.
Gen R, Addetia A, Asarnow D, Park Y, Quispe J, Chan M, et al.
bioRxiv . 2025 Jan; PMID: 39868184
SARS-CoV-2 nonstructural protein 1 (nsp1) promotes innate immune evasion by inhibiting host translation in human cells. However, the role of nsp1 in other host species remains elusive, especially in bats...
3.
Chao C, Sprouse K, Miranda M, Catanzaro N, Hubbard M, Addetia A, et al.
Cell Rep . 2024 Dec; 43(12):115036. PMID: 39644492
Middle East respiratory syndrome coronavirus (MERS-CoV) is a betacoronavirus that causes severe respiratory illness in humans. There are no licensed vaccines against MERS-CoV and only a few candidates in phase...
4.
Ragotte R, Tortorici M, Catanzaro N, Addetia A, Coventry B, Froggatt H, et al.
bioRxiv . 2024 Nov; PMID: 39574666
Middle-East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic pathogen with 36% case-fatality rate in humans. No vaccines or specific therapeutics are currently approved to use in humans or the camel...
5.
Rosen L, Tortorici M, De Marco A, Pinto D, Foreman W, Taylor A, et al.
Cell . 2024 Oct; 187(25):7196-7213.e26. PMID: 39383863
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has resulted in viral escape from clinically authorized monoclonal antibodies (mAbs), creating a need for mAbs that are resilient to epitope diversification....
6.
Park Y, Liu C, Lee J, Brown J, Ma C, Liu P, et al.
bioRxiv . 2024 Sep; PMID: 39253417
DPP4 was considered a canonical receptor for merbecoviruses until the recent discovery of African bat-borne MERS-related coronaviruses using ACE2. The extent and diversity with which merbecoviruses engage ACE2 and their...
7.
Addetia A, Stewart C, Seo A, Sprouse K, Asiri A, Al-Mozaini M, et al.
Cell Rep . 2024 Jul; 43(8):114530. PMID: 39058596
Middle East respiratory syndrome coronavirus (MERS-CoV) first emerged in 2012 and causes human infections in endemic regions. Vaccines and therapeutics in development against MERS-CoV focus on the spike (S) glycoprotein...
8.
McCallum M, Park Y, Stewart C, Sprouse K, Addetia A, Brown J, et al.
Cell . 2024 Jul; 187(16):4231-4245.e13. PMID: 38964328
The human coronavirus HKU1 spike (S) glycoprotein engages host cell surface sialoglycans and transmembrane protease serine 2 (TMPRSS2) to initiate infection. The molecular basis of HKU1 binding to TMPRSS2 and...
9.
Addetia A, Stewart C, Seo A, Sprouse K, Asiri A, Al-Mozaini M, et al.
bioRxiv . 2024 Apr; PMID: 38617298
Middle-East respiratory syndrome coronavirus (MERS-CoV) first emerged in 2012 and causes human infections in endemic regions. Most vaccines and therapeutics in development against MERS-CoV focus on the spike (S) glycoprotein...
10.
Chao C, Sprouse K, Miranda M, Catanzaro N, Hubbard M, Addetia A, et al.
bioRxiv . 2024 Apr; PMID: 38558973
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic betacoronavirus that causes severe and often lethal respiratory illness in humans. The MERS-CoV spike (S) protein is the viral fusogen and...