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Ami Tsuchida

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Articles 23
Citations 497
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Recent Articles
1.
Tsuchida A, Goubet M, Boutinaud P, Astafeva I, Nozais V, Herve P, et al.
Sci Rep . 2024 Dec; 14(1):30901. PMID: 39730628
Cerebral microbleeds (CMB) represent a feature of cerebral small vessel disease (cSVD), a prominent vascular contributor to age-related cognitive decline, dementia, and stroke. They are visible as spherical hypointense signals...
2.
Debette S, Caro I, Western D, Namba S, Sun N, Kawaguchi S, et al.
Res Sq . 2024 Jul; PMID: 39011113
Cerebral small vessel disease (cSVD) is a leading cause of stroke and dementia with no specific mechanism-based treatment. We used Mendelian randomization to combine a unique cerebrospinal fluid (CSF) and...
3.
Le Grand Q, Tsuchida A, Koch A, Imtiaz M, Aziz N, Vigneron C, et al.
Mol Psychiatry . 2024 May; 29(11):3567-3579. PMID: 38811690
Cerebral small vessel disease (cSVD) is a leading cause of stroke and dementia. Genetic risk loci for white matter hyperintensities (WMH), the most common MRI-marker of cSVD in older age,...
4.
Bercu A, Dufouil C, Debette S, Joliot M, Tsuchida A, Helmer C, et al.
Alzheimers Dement (Amst) . 2024 May; 16(2):e12578. PMID: 38800122
Abstract: The utility of brain magnetic resonance imaging (MRI) for predicting dementia is debated. We evaluated the added value of repeated brain MRI, including atrophy and cerebral small vessel disease...
5.
Knol M, Poot R, Evans T, Satizabal C, Mishra A, Sargurupremraj M, et al.
Cell Rep Med . 2024 May; 5(5):101529. PMID: 38703765
The size of the human head is highly heritable, but genetic drivers of its variation within the general population remain unmapped. We perform a genome-wide association study on head size...
6.
Tsuchida A, Boutinaud P, Verrecchia V, Tzourio C, Debette S, Joliot M
Hum Brain Mapp . 2023 Dec; 45(1):e26548. PMID: 38050769
White matter hyperintensities (WMHs) are well-established markers of cerebral small vessel disease, and are associated with an increased risk of stroke, dementia, and mortality. Although their prevalence increases with age,...
7.
Reboucas S, Crivello F, Tsuchida A, Tzourio C, Schweitzer C, Korobelnik J, et al.
Hum Brain Mapp . 2023 Jul; 44(13):4722-4737. PMID: 37401639
Given the anatomical and functional similarities between the retina and the brain, the retina could be a "window" for viewing brain structures. We investigated the association between retinal nerve fiber...
8.
Duperron M, Knol M, Le Grand Q, Evans T, Mishra A, Tsuchida A, et al.
Nat Med . 2023 Apr; 29(4):950-962. PMID: 37069360
Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia. Genome-wide association studies in up...
9.
Le Grand Q, Satizabal C, Sargurupremraj M, Mishra A, Soumare A, Laurent A, et al.
Biol Psychiatry Cogn Neurosci Neuroimaging . 2021 Oct; 7(6):616-628. PMID: 34700051
Background: Subcortical brain structures play a key role in pathological processes of age-related neurodegenerative disorders. Mounting evidence also suggests that early-life factors may have an impact on the development of...
10.
Cremona S, Zago L, Mellet E, Petit L, Laurent A, Pepe A, et al.
Hum Brain Mapp . 2021 Aug; 42(16):5264-5277. PMID: 34453474
The relationship between hippocampal subfield volumetry and verbal list-learning test outcomes have mostly been studied in clinical and elderly populations, and remain controversial. For the first time, we characterized a...