Ameya R Kirtane
Overview
Explore the profile of Ameya R Kirtane including associated specialties, affiliations and a list of published articles.
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35
Citations
606
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Recent Articles
1.
Linderman S, DeRidder L, Sanjurjo L, Foote M, Alonso M, Kirtane A, et al.
Nat Rev Clin Oncol
. 2025 Mar;
PMID: 40050505
The targeted delivery of immunotherapies to tumours using tumour-responsive nanomaterials is a promising area of cancer research with the potential to address the limitations of systemic administration such as on-target...
2.
Kirtane A, Bi J, Rajesh N, Tang C, Jimenez M, Witt E, et al.
Nat Biomed Eng
. 2025 Feb;
PMID: 40011582
Patients undergoing radiation therapy experience debilitating side effects because of toxicity arising from radiation-induced DNA strand breaks in normal peritumoural cells. Here, inspired by the ability of tardigrades to resist...
3.
DeRidder L, Hare K, Lopes A, Jenkins J, Fitzgerald N, MacPherson E, et al.
Med
. 2024 Apr;
5(7):780-796.e10.
PMID: 38663403
Background: Dosing of chemotherapies is often calculated according to the weight and/or height of the patient or equations derived from these, such as body surface area (BSA). Such calculations fail...
4.
Shi Y, Reker D, Byrne J, Kirtane A, Hess K, Wang Z, et al.
Nat Biomed Eng
. 2024 Feb;
8(3):278-290.
PMID: 38378821
In vitro systems that accurately model in vivo conditions in the gastrointestinal tract may aid the development of oral drugs with greater bioavailability. Here we show that the interaction profiles...
5.
Kirtane A, Tang C, Freitas D, Bernstock J, Traverso G
Curr Opin Immunol
. 2023 Sep;
85:102388.
PMID: 37776698
mRNA vaccines have played a critical role in controlling the SARS-CoV-2 pandemic, and are being actively studied for use in other diseases. There is a growing interest in applying mRNA...
6.
Kim H, Kirtane A, Kim N, Rajesh N, Tang C, Ishida K, et al.
AAPS J
. 2023 Aug;
25(5):81.
PMID: 37589795
mRNA vaccines can be translated into protein antigens, in vivo, to effectively induce humoral and cellular immunity against these proteins. While current mRNA vaccines have generated potent immune responses, the...
7.
Li Y, Lee J, Kirtane A, Li M, Coffey 3rd C, Hess K, et al.
Adv Healthc Mater
. 2023 Jun;
12(27):e2301033.
PMID: 37314859
Patient adherence to chronic therapies can be suboptimal, leading to poor therapeutic outcomes. Dosage forms that enable reduction in dosing frequency stand to improve patient adherence. Variation in gastrointestinal transit...
8.
Kirtane A, Karavasili C, Wahane A, Freitas D, Booz K, Le D, et al.
Sci Adv
. 2022 May;
8(21):eabm8478.
PMID: 35622910
Administering medicines to 0- to 5-year-old children in a resource-limited environment requires dosage forms that circumvent swallowing solids, avoid on-field reconstitution, and are thermostable, cheap, versatile, and taste masking. We...
9.
Lee S, Wan Q, Wentworth A, Ballinger I, Ishida K, Collins J, et al.
Sci Adv
. 2021 Nov;
7(48):eabj4624.
PMID: 34826238
Diurnal variation in enzymes, hormones, and other biological mediators has long been recognized in mammalian physiology. Developments in pharmacobiology over the past few decades have shown that timing drug delivery...
10.
Byrne J, Young C, Chu J, Pursley J, Chen M, Wentworth A, et al.
Adv Sci (Weinh)
. 2021 Jul;
8(12):2100510.
PMID: 34194950
Cancer patients undergoing therapeutic radiation routinely develop injury of the adjacent gastrointestinal (GI) tract mucosa due to treatment. To reduce radiation dose to critical GI structures including the rectum and...