Amedeo Rapuano
Overview
Explore the profile of Amedeo Rapuano including associated specialties, affiliations and a list of published articles.
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7
Citations
51
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Recent Articles
1.
Lee T, Li A, Rapuano A, Mantis J, Eid T, Seyfried T, et al.
Neurobiol Dis
. 2020 Nov;
147:105152.
PMID: 33153970
The neuropathology of hippocampal seizure foci in human temporal lobe epilepsy (TLE) and several animal models of epilepsy reveal extensive neuronal loss along with astrocyte and microglial activation. Studies of...
2.
Kim J, Goodrich J, Situ R, Rapuano A, Hetherington H, Du F, et al.
J Neuropathol Exp Neurol
. 2020 May;
79(6):605-617.
PMID: 32386412
The neuropathology of mild traumatic brain injury in humans resulting from exposure to explosive blast is poorly understood as this condition is rarely fatal. A large animal model may better...
3.
Dhaher R, Chen E, Perez E, Rapuano A, Sandhu M, Gruenbaum S, et al.
Nutr Neurosci
. 2020 Jan;
25(1):64-69.
PMID: 31900092
Glutamine synthetase (GS) is the only enzyme known to synthesize significant amounts of glutamine in mammals, and loss of GS in the hippocampus has been implicated in the pathophysiology of...
4.
Gruenbaum S, Dhaher R, Rapuano A, Zaveri H, Tang A, de Lanerolle N, et al.
J Neurosurg Anesthesiol
. 2018 Apr;
31(2):247-256.
PMID: 29620688
Background: The essential branched-chain amino acids (BCAAs) leucine, isoleucine, and valine have recently emerged as a potential novel treatment for medically refractory epilepsy. Blood-derived BCAAs can readily enter the brain,...
5.
Pearce P, Wu Y, Rapuano A, Kelly K, de Lanerolle N, Pan J
Epilepsia
. 2016 Dec;
57(12):1978-1986.
PMID: 27943308
Objective: In vivo studies of epilepsy typically use prolonged status epilepticus to generate recurrent seizures. However, reports on variable status duration have found discrete differences in injury after 40-50 min...
6.
Goodrich J, Kim J, Situ R, Taylor W, Westmoreland T, Du F, et al.
Acta Neuropathol Commun
. 2016 Nov;
4(1):124.
PMID: 27884214
Mild traumatic brain injury (mTBI) is the signature injury in warfighters exposed to explosive blasts. The pathology underlying mTBI is poorly understood, as this condition is rarely fatal and thus...
7.
Wu Y, Pearce P, Rapuano A, Hitchens T, de Lanerolle N, Pan J
J Cereb Blood Flow Metab
. 2015 Jun;
35(11):1862-70.
PMID: 26104287
There is little experimental in vivo data on how differences in seizure duration in experimental status epilepticus influence metabolic injury. This is of interest given that in humans, status duration...