Amber K OConnor
Overview
Explore the profile of Amber K OConnor including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
643
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wu M, Harafuji N, OConnor A, Caldovic L, Guay-Woodford L
Front Mol Biosci
. 2023 Jan;
9:946344.
PMID: 36710876
Transcription factor Ap2b (TFAP2B), an AP-2 family transcription factor, binds to the palindromic consensus DNA sequence, 5'-GCCNGGC-3'. Mice lacking functional gene die in the perinatal or neonatal period with cystic...
2.
Yang C, Harafuji N, OConnor A, Kesterson R, Watts J, Majmundar A, et al.
Sci Rep
. 2021 Sep;
11(1):18274.
PMID: 34521872
Mutation of the Cys1 gene underlies the renal cystic disease in the Cys1 (cpk) mouse that phenocopies human autosomal recessive polycystic kidney disease (ARPKD). Cystin, the protein product of Cys1,...
3.
Rockwell D, OConnor A, Bentley-Ford M, Haycraft C, Croyle M, Brewer K, et al.
Dev Dyn
. 2021 Mar;
251(9):1524-1534.
PMID: 33728725
Background: Genetic tools to study gene function and the fate of cells in the anterior limb bud are very limited. Results: We describe a transgenic mouse line expressing CreER from...
4.
Schultz M, Holdbrooks A, Chakraborty A, Grizzle W, Landen C, Buchsbaum D, et al.
Cancer Res
. 2016 May;
76(13):3978-88.
PMID: 27216178
The glycosyltransferase ST6Gal-I, which adds α2-6-linked sialic acids to substrate glycoproteins, has been implicated in carcinogenesis; however, the nature of its pathogenic role remains poorly understood. Here we show that...
5.
Lee C, OConnor A, Yang C, Tate J, Schoeb T, Flint J, et al.
Physiol Rep
. 2015 Aug;
3(8).
PMID: 26320214
Polycystic kidney disease (PKD) is transmitted as either an autosomal dominant or recessive trait and is a major cause of renal failure and liver fibrosis. The cpk mouse model of...
6.
Boddu R, Yang C, OConnor A, Hendrickson R, Boone B, Cui X, et al.
J Mol Med (Berl)
. 2014 Jul;
92(10):1045-56.
PMID: 24984783
Autosomal recessive polycystic kidney disease (ARPKD) results from mutations in the human PKHD1 gene. Both this gene, and its mouse ortholog, Pkhd1, are primarily expressed in renal and biliary ductal...
7.
OConnor A, Malarkey E, Berbari N, Croyle M, Haycraft C, Bell P, et al.
Cilia
. 2013 Jul;
2(1):8.
PMID: 23819925
Background: Cilia are found on nearly every cell type in the mammalian body, and have been historically classified as either motile or immotile. Motile cilia are important for fluid and...
8.
Sharma N, Malarkey E, Berbari N, OConnor A, Vanden Heuvel G, Mrug M, et al.
J Am Soc Nephrol
. 2013 Feb;
24(3):456-64.
PMID: 23411784
Disrupting the function of cilia in mouse kidneys results in rapid or slow progression of cystic disease depending on whether the animals are juveniles or adults, respectively. Renal injury can...
9.
Croyle M, Lehman J, OConnor A, Wong S, Malarkey E, Iribarne D, et al.
Development
. 2011 Mar;
138(9):1675-85.
PMID: 21429982
Skin and hair follicle morphogenesis and homeostasis require the integration of multiple signaling pathways, including Hedgehog (Hh) and Wingless (Wnt), and oriented cell divisions, all of which have been associated...
10.
OConnor A, Kesterson R, Yoder B
Methods Cell Biol
. 2010 Apr;
93:305-30.
PMID: 20409823
The list of human disordered associated with cilia dysfunction, the ciliopathies, continues to highlight the importance of understanding the many roles of the long overlooked primary cilium. Much of the...