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Amaury Francois

Explore the profile of Amaury Francois including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 1037
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Recent Articles
1.
Borie A, Dromard Y, Chakraborty P, Fontanaud P, Andre E, Francois A, et al.
Cell Rep Med . 2024 Oct; 5(11):101781. PMID: 39423809
Confronting oxytocin and vasopressin deficits in autism spectrum disorders and rare syndromes brought promises and disappointments for the treatment of social disabilities. We searched downstream of oxytocin and vasopressin for...
2.
Picard E, Kerckhove N, Francois A, Boudieu L, Billard E, Carvalho F, et al.
Br J Pharmacol . 2022 Sep; 180(4):385-400. PMID: 36131381
Background And Purpose: T-type calcium channels, mainly the Ca 3.2 subtype, are important contributors to the nociceptive signalling pathway. We investigated their involvement in inflammation and related pain-like symptoms. Experimental...
3.
Huzard D, Martin M, Maingret F, Chemin J, Jeanneteau F, Mery P, et al.
Sci Adv . 2022 Jun; 8(26):eabo7566. PMID: 35767616
Affective touch is necessary for proper neurodevelopment and sociability. However, it remains unclear how the neurons innervating the skin detect affective and social behaviors. The C low-threshold mechanoreceptors (C-LTMRs), a...
4.
Duan L, Hope J, Guo S, Ong Q, Francois A, Kaplan L, et al.
ACS Synth Biol . 2018 Jul; 7(7):1685-1693. PMID: 29975841
Nerve growth factor/tropomyosin receptor kinase A (NGF/TrkA) signaling plays a key role in neuronal development, function, survival, and growth. The pathway is implicated in neurodegenerative disorders including Alzheimer's disease, chronic...
5.
Wang D, Tawfik V, Corder G, Low S, Francois A, Basbaum A, et al.
Neuron . 2018 Mar; 98(1):90-108.e5. PMID: 29576387
Cellular interactions between delta and mu opioid receptors (DORs and MORs), including heteromerization, are thought to regulate opioid analgesia. However, the identity of the nociceptive neurons in which such interactions...
6.
Francois A, Scherrer G
Handb Exp Pharmacol . 2017 Oct; 247:87-114. PMID: 28993838
The functional diversity of primary afferent neurons of the dorsal root ganglia (DRG) generates a variety of qualitatively and quantitatively distinct somatosensory experiences, from shooting pain to pleasant touch. In...
7.
Bardoni R, Tawfik V, Wang D, Francois A, Solorzano C, Shuster S, et al.
Neuron . 2017 Sep; 81(6):1443. PMID: 28898633
No abstract available.
8.
Francois A, Low S, Sypek E, Christensen A, Sotoudeh C, Beier K, et al.
Neuron . 2017 Feb; 93(4):822-839.e6. PMID: 28162807
Pain thresholds are, in part, set as a function of emotional and internal states by descending modulation of nociceptive transmission in the spinal cord. Neurons of the rostral ventromedial medulla...
9.
Christensen A, Iyer S, Francois A, Vyas S, Ramakrishnan C, Vesuna S, et al.
Cell Rep . 2016 Nov; 17(6):1699-1710. PMID: 27806306
Spinal dorsal horn circuits receive, process, and transmit somatosensory information. To understand how specific components of these circuits contribute to behavior, it is critical to be able to directly modulate...
10.
Bourinet E, Francois A, Laffray S
Pain . 2016 Jan; 157 Suppl 1:S15-S22. PMID: 26785151
Pain is a quite frequent complaint accompanying numerous pathologies. Among these pathological cases, numerous neuropathies are retrieved with identified etiologies (chemotherapies, diabetes, surgeries…) and also more diffuse syndromes such as...