Amarjyoti Das Mahapatra
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Explore the profile of Amarjyoti Das Mahapatra including associated specialties, affiliations and a list of published articles.
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9
Citations
33
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Recent Articles
1.
Copper and Manganese Complexes of Pyridinecarboxaldimine Induce Oxidative Cell Death in Cancer Cells
Vechalapu S, Kumar R, Sachan S, Shaikh K, Mahapatra A, Draksharapu A, et al.
ACS Appl Bio Mater
. 2024 Sep;
7(10):6696-6705.
PMID: 39240687
Leveraging the versatile redox behavior of transition metal complexes with heterocyclic ligands offers significant potential for discovering new anticancer therapeutics. This study presents a systematic investigation of a pyridinecarboxaldimine ligand...
2.
Diasi M, Singh R, Mahapatra A, L R, Patel H, Ganatra H, et al.
RSC Adv
. 2024 Feb;
14(10):6972-6984.
PMID: 38414993
In this work, we have studied the ability of urease immobilized on glutaraldehyde crosslinked chitosan coated magnetic iron oxide nanoparticles (Urease/GA/CS/MIONPs), for the hitherto unreported comparative hydrolysis of urea in...
3.
Ratrey P, Mahapatra A, Pandit S, Hadianawala M, Majhi S, Mishra A, et al.
RSC Adv
. 2022 Apr;
11(46):28581-28592.
PMID: 35478531
Hybrid antimicrobials that combine the effect of two or more agents represent a promising antibacterial therapeutic strategy. In this work, we have synthesized -(4-(4-(methylsulfonyl)phenyl)-5-phenylthiazol-2-yl)benzenesulfonamide derivatives that combine thiazole and sulfonamide,...
4.
Mahapatra A, Choubey R, Datta B
Molecules
. 2020 Dec;
25(23).
PMID: 33255197
The enzyme soluble epoxide hydrolase (sEH) plays a central role in metabolism of bioactive lipid signaling molecules. The substrate-specific hydrolase activity of sEH converts epoxyeicosatrienoic acids (EETs) to less bioactive...
5.
Mahapatra A, Queen A, Yousuf M, Khan P, Hussain A, Rehman M, et al.
J Biomol Struct Dyn
. 2020 Nov;
40(7):3144-3154.
PMID: 33183174
Inhibitors of carbonic anhydrase (CAIs) hold promise for addressing various diseases, including cancer, diabetes, and other metabolic syndromes. CAV is the only isoform present in the mitochondria and is considered...
6.
Roy S, Mahapatra A, Mohammad T, Gupta P, Alajmi M, Hussain A, et al.
Pharmaceuticals (Basel)
. 2020 Jun;
13(6).
PMID: 32526899
Sphingosine kinase 1 (SphK1) is one of the well-studied drug targets for cancer and inflammatory diseases. Recently discovered small-molecule inhibitors of SphK1 have been recommended in cancer therapeutics; however, selectivity...
7.
Lynn Punzalan L, Jiang L, Mao D, Mahapatra A, Sato S, Takemoto Y, et al.
Cell Chem Biol
. 2020 May;
27(6):708-718.e10.
PMID: 32402240
Pharmacophore-focused chemical libraries are continuously being created in drug discovery programs, yet screening assays to maximize the usage of such libraries are not fully explored. Here, we report a chemical...
8.
Idrees D, Hadianawala M, Mahapatra A, Datta B, Roy S, Ahamad S, et al.
Int J Biol Macromol
. 2018 Apr;
115:961-969.
PMID: 29704602
Selective carbonic anhydrase (CA) inhibitors have gained a lot of importance owing to the implication of specific isoforms of CA in certain diseases like glaucoma, leukemia, cystic fibrosis, and epilepsy....
9.
Hadianawala M, Mahapatra A, Yadav J, Datta B
J Mol Model
. 2018 Feb;
24(3):69.
PMID: 29480373
Designed multi-target ligand (DML) is an emerging strategy for the development of new drugs and involves the engagement of multiple targets with the same moiety. In the context of NSAIDs...