Amanda L Ziegler
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Explore the profile of Amanda L Ziegler including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
97
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0
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Recent Articles
1.
Rose E, Simon J, Gomez-Martinez I, Magness S, Odle J, Blikslager A, et al.
Am J Physiol Gastrointest Liver Physiol
. 2025 Jan;
328(3):G182-G196.
PMID: 39853303
Intestinal ischemic injury damages the epithelial barrier and predisposes patients to life-threatening sepsis unless that barrier is rapidly restored. There is an age dependency in intestinal recovery in that neonates...
2.
Rose E, Simon J, Gomez-Martinez I, Magness S, Odle J, Blikslager A, et al.
bioRxiv
. 2024 Jul;
PMID: 38979337
New & Noteworthy: These studies validate an approach to identify and predict upstream regulation of restituting epithelium in a unique pig intestinal ischemic injury model. Identification of potential molecular mediators...
3.
Boston T, Wang F, Lin X, Kim S, Fellner V, Scott M, et al.
J Anim Sci Biotechnol
. 2024 Jun;
15(1):88.
PMID: 38867260
Background: Weaning stress reduces growth performance and health of young pigs due in part to an abrupt change in diets from highly digestible milk to fibrous plant-based feedstuffs. This study...
4.
Caldwell M, Cook C, Mariant C, Touvron M, Odle J, Blikslager A, et al.
STAR Protoc
. 2024 May;
5(2):103057.
PMID: 38762883
Here, we present our protocol to culture enteric glial cells from the submucosal and myenteric plexus of neonatal and juvenile pig colons. We describe steps for colon isolation, microdissection, and...
5.
Ziegler A, Caldwell M, Craig S, Hellstrom E, Sheridan A, Touvron M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2023 Dec;
326(3):G228-G246.
PMID: 38147796
Ischemic damage to the intestinal epithelial barrier, such as in necrotizing enterocolitis or small intestinal volvulus, is associated with higher mortality rates in younger patients. We have recently reported a...
6.
Rivera K, Bliton R, Burclaff J, Czerwinski M, Liu J, Trueblood J, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Aug;
16(5):823-846.
PMID: 37562653
Background And Aims: Hypoxia in the intestinal epithelium can be caused by acute ischemic events or chronic inflammation in which immune cell infiltration produces inflammatory hypoxia starving the mucosa of...
7.
Rivera K, Bliton R, Burclaff J, Czerwinski M, Liu J, Trueblood J, et al.
bioRxiv
. 2023 Feb;
PMID: 36778265
Background & Aims: Hypoxia in the intestinal epithelium can be caused by acute ischemic events or conditions like Inflammatory Bowel Disease (IBD) where immune cell infiltration produces 'inflammatory hypoxia', a...
8.
Boger K, Sheridan A, Ziegler A, Blikslager A
Tissue Barriers
. 2022 Jun;
11(2):2087454.
PMID: 35695206
The intestinal epithelial barrier is susceptible to injury from insults, such as ischemia or infectious disease. The epithelium's ability to repair wounded regions is critical to maintaining barrier integrity. Mechanisms...
9.
Erwin S, Clark M, Dechant J, Aitken M, Hassel D, Blikslager A, et al.
Animals (Basel)
. 2022 Jun;
12(11).
PMID: 35681837
Lower survival has been reported in foals than adults with small intestinal strangulating obstruction (SISO), but age-dependent outcomes have not been examined directly. Hospital records were collected from five US...
10.
Rose E, Blikslager A, Ziegler A
Front Vet Sci
. 2022 Apr;
9:834598.
PMID: 35400098
In the United States, gastrointestinal disorders account for in excess of $130 billion in healthcare expenditures and 22 million hospitalizations annually. Many of these disorders, including necrotizing enterocolitis of infants,...