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Amanda L Turner

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Citations 274
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Recent Articles
1.
Cook A, Pobjoy J, Steidl S, Durr M, Braine E, Turner A, et al.
Arthritis Res Ther . 2012 Sep; 14(5):R199. PMID: 22995428
Introduction: Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been shown to be important in the development of inflammatory models of rheumatoid arthritis and there is encouraging data that its blockade may have...
2.
Cook A, Turner A, Braine E, Pobjoy J, Lenzo J, Hamilton J
Arthritis Rheum . 2011 Aug; 63(8):2340-51. PMID: 21809323
Objective: Even though there are clinical trials assessing granulocyte-macrophage colony-stimulating factor (GM-CSF) blockade in rheumatoid arthritis (RA), questions remain as to how GM-CSF acts as a proinflammatory cytokine. The aims...
3.
Lenzo J, Turner A, Cook A, Vlahos R, Anderson G, Reynolds E, et al.
Immunol Cell Biol . 2011 Jul; 90(4):429-40. PMID: 21727904
There is recent interest in the role of monocyte/macrophage subpopulations in pathology. How the hemopoietic growth factors, macrophage-colony stimulating factor (M-CSF or CSF-1) and granulocyte macrophage (GM)-CSF, regulate their in...
4.
Cook A, De Nardo C, Braine E, Turner A, Vlahos R, Way K, et al.
Arthritis Res Ther . 2010 Mar; 12(2):R37. PMID: 20196869
Introduction: Urokinase-type plasminogen activator (u-PA) has been implicated in fibrinolysis, cell migration, latent cytokine activation, cell activation, T-cell activation, and tissue remodeling, all of which are involved in the development...
5.
Cook A, Vlahos R, Massa C, Braine E, Lenzo J, Turner A, et al.
Thromb Haemost . 2006 Apr; 95(4):659-67. PMID: 16601837
There are two plasminogen activators (PAs), urokinase type-PA (u-PA) and tissue type-PA (t-PA). While u-PA is considered to be involved in cellular migration and tissue remodeling and t-PA in fibrinolysis,...
6.
Kitching A, Turner A, Wilson G, Semple T, Odobasic D, Timoshanko J, et al.
J Am Soc Nephrol . 2005 May; 16(7):2023-33. PMID: 15888563
Experimental crescentic glomerulonephritis (GN) is characterized by T helper 1 (Th1) directed nephritogenic immune responses and cell-mediated glomerular injury. IL-12p40, the common cytokine chain for both IL-12 and IL-23, is...
7.
Kitching A, Turner A, Wilson G, Edgtton K, Tipping P, Holdsworth S
J Am Soc Nephrol . 2004 Sep; 15(9):2373-82. PMID: 15339986
IL-13 is produced by T helper 2 (Th2) cells, has a role in stimulating Th2-mediated injury, alters humoral responses, and may directly suppress macrophage and neutrophil function. In immune renal...
8.
Kitching A, Turner A, Semple T, Li M, Edgtton K, Wilson G, et al.
J Am Soc Nephrol . 2004 Jun; 15(7):1764-74. PMID: 15213264
IL-12 and IFN-gamma play key roles in murine lupus and planted antigen models of glomerulonephritis. However, their roles in renal organ-specific autoimmunity are unknown. To establish the roles of endogenous...
9.
Kitching A, Huang X, Turner A, Tipping P, Dunn A, Holdsworth S
J Am Soc Nephrol . 2002 Jan; 13(2):350-358. PMID: 11805162
Proliferative glomerulonephritis in humans is characterized by the presence of leukocytes in glomeruli. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) can potentially stimulate or affect T cell, macrophage,...