Amanda K Purdy
Overview
Explore the profile of Amanda K Purdy including associated specialties, affiliations and a list of published articles.
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7
Citations
269
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0
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Recent Articles
1.
Purdy A, Alvarez Arias D, Oshinsky J, James A, Serebriiskii I, Campbell K
J Immunol
. 2014 Sep;
193(9):4675-83.
PMID: 25238755
Stable surface expression of human inhibitory killer cell Ig-like receptors (KIRs) is critical for controlling NK cell function and maintaining NK cell tolerance toward normal MHC class I(+) cells. Our...
2.
Purdy A, Campbell K
Zhongguo Fei Ai Za Zhi
. 2011 Jun;
13(7):731-6.
PMID: 21644387
No abstract available.
3.
Miah S, Purdy A, Rodin N, MacFarlane 4th A, Oshinsky J, Alvarez-Arias D, et al.
J Immunol
. 2011 Jan;
186(5):2959-69.
PMID: 21270397
Killer cell Ig-like receptor (KIR) with two Ig-like domains and a long cytoplasmic domain 4 (2DL4; CD158d) is a unique KIR expressed on human NK cells, which stimulates cytokine production,...
4.
Campbell K, Purdy A
Immunology
. 2011 Jan;
132(3):315-25.
PMID: 21214544
Stimulation or tolerance of natural killer (NK) cells is achieved through a cross-talk of signals derived from cell surface activating and inhibitory receptors. Killer cell immunoglobulin-like receptors (KIR) are a...
5.
Purdy A, Campbell K
Methods Mol Biol
. 2009 Dec;
612:223-31.
PMID: 20033644
Natural killer (NK) cell lines are difficult to transfect using standard techniques, which limits the ability to establish long-term knockdown of proteins with short-hairpin (sh)RNAs. We have developed a method...
6.
Purdy A, Campbell K
Cancer Biol Ther
. 2009 Nov;
8(23):2211-20.
PMID: 19923897
Natural killer (NK) cells are innate immune effector cells that make up approximately 10-15% of the peripheral blood lymphocytes in humans and are primarily involved in immunosurveillance to eliminate transformed...
7.
Purdy A, Campbell K
J Immunol
. 2009 Nov;
183(11):7234-43.
PMID: 19915046
Src homology region 2-containing protein tyrosine phosphatase-2 (SHP-2) is required for full activation of Ras/ERK in many cytokine and growth factor receptor signaling pathways. In contrast, SHP-2 inhibits activation of...