Amanda K P Mann
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Explore the profile of Amanda K P Mann including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
82
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Recent Articles
1.
Li Y, Mann A, Zhang D, Yang Z
Pharmaceutics
. 2021 Aug;
13(8).
PMID: 34452269
Presently, a large number of drug molecules in development are BCS class II or IV compounds with poor aqueous solubility. Various novel solubilization techniques have been used to enhance drug...
2.
Yang R, Mann A, Van Duong T, Ormes J, Okoh G, Hermans A, et al.
Mol Pharm
. 2021 Mar;
18(5):2066-2081.
PMID: 33784104
Dissolution of amorphous solid dispersions (ASD) can lead to the formation of amorphous drug-rich nano species (nanodroplets) via liquid-liquid phase separation or glass-liquid phase separation when the drug concentration exceeds...
3.
Schenck L, Mann A, Liu Z, Milewski M, Zhang S, Ren J, et al.
Int J Pharm
. 2019 Jan;
559:147-155.
PMID: 30654058
Amorphous solid dispersions are a promising option for managing compounds with poor aqueous solubility. However, for compounds with high melting points, thermal stability limitations, or poor solubility in volatile solvents,...
4.
Mann A, Schenck L, Koynov A, Rumondor A, Jin X, Marota M, et al.
J Pharm Sci
. 2017 Jul;
107(1):183-191.
PMID: 28711592
Many small-molecule active pharmaceutical ingredients (APIs) exhibit low aqueous solubility and benefit from generation of amorphous dispersions of the API and polymer to improve their dissolution properties. Spray drying and...
5.
Purohit H, Ormes J, Saboo S, Su Y, Lamm M, Mann A, et al.
Pharm Res
. 2017 Apr;
34(7):1364-1377.
PMID: 28455777
Purpose: Miscibility between the drug and the polymer in an amorphous solid dispersion (ASD) is considered to be one of the most important factors impacting the solid state stability and...
6.
Wu Z, Jiang D, Mann A, Mullins D, Qiao Z, Allard L, et al.
J Am Chem Soc
. 2014 Apr;
136(16):6111-22.
PMID: 24702268
The effect of thiolate ligands was explored on the catalysis of CeO2 rod supported Au25(SR)18 (SR = -SCH2CH2Ph) by using CO oxidation as a probe reaction. Reaction kinetic tests, in...
7.
Mann B, Mann A, Skrabalak S, Novotny M
Anal Chem
. 2013 Jan;
85(3):1905-12.
PMID: 23278114
A new, mechanically stable silica microparticle with macrosized internal pores (1.6 μm particles with 100 nm pores) has been developed for chromatography. The particles are characterized by an extensive network...
8.
Mann A, Wicker S, Skrabalak S
Adv Mater
. 2012 Sep;
24(46):6186-91.
PMID: 22961891
NaInS(2) , a H(2) -evolving photocatalyst, is synthesized as single-crystalline hexagonal plates by coupling a molten salt synthesis with ultrasonic spray pyrolysis (USP) for the first time. USP NaInS(2) films...
9.
Mann A, Steinmiller E, Skrabalak S
Dalton Trans
. 2012 Apr;
41(26):7939-45.
PMID: 22517507
Polycrystalline microspheres and single-crystalline microplates of Bi(2)WO(6) have been synthesized by ultrasonic spray pyrolysis. Herein, these materials are evaluated as photocatalysts for the visible light mediated degradation of rhodamine B,...