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Amanda H Y Lin

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Articles 7
Citations 148
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Recent Articles
1.
Lin A, Sun H, Paudel O, Lin M, Sham J
Cardiovasc Res . 2016 Mar; 111(1):94-104. PMID: 27013634
Aims: Store-operated Ca(2+) entry (SOCE) contributes to a multitude of physiological and pathophysiological functions in pulmonary vasculatures. SOCE attributable to inositol 1,4,5-trisphosphate receptor (InsP3R)-gated Ca(2+) store has been studied extensively,...
2.
Huang C, Hu J, Subedi K, Lin A, Paudel O, Ran P, et al.
Cell Physiol Biochem . 2015 Nov; 37(5):2043-59. PMID: 26584302
Background/aims: Adenosine diphosphate ribose (ADPR), a product of β-NAD+ metabolism generated by the multifunctional enzyme CD38, is recognized as a novel signaling molecule. The catalytic site of CD38 orients extracellularly...
3.
Lin A, Shang Y, Mitzner W, Sham J, Tang W
Am J Respir Cell Mol Biol . 2015 Jul; 54(2):241-9. PMID: 26181301
Airway hyperresponsiveness (AHR) is a hallmark feature in asthma characterized by exaggerated airway contractile response to stimuli due to increased airway sensitivity and chronic airway remodeling. We have previously shown...
4.
Lin A, Li R, Ho E, Leung G, Leung S, Vanhoutte P, et al.
PLoS One . 2013 May; 8(4):e63199. PMID: 23646196
Rapid non-genomic effects of 17β-estradiol are elicited by the activation of different estrogen receptor-α isoforms. Presence of surface binding sites for estrogen have been identified in cells transfected with full-length...
5.
Jiang Y, Lin A, Xia Y, Lee S, Paudel O, Sun H, et al.
J Biol Chem . 2013 Feb; 288(15):10381-94. PMID: 23443655
Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most potent Ca(2+)-mobilizing messenger that releases Ca(2+) from endolysosomal organelles. Recent studies showed that NAADP-induced Ca(2+) release is mediated by the two-pore...
6.
Yang X, Lin A, Hughes J, Flavahan N, Cao Y, Liedtke W, et al.
Am J Physiol Lung Cell Mol Physiol . 2011 Dec; 302(6):L555-68. PMID: 22207590
Chronic hypoxia causes pulmonary hypertension with vascular remodeling, increase in vascular tone, and altered reactivity to agonists. These changes involve alterations in multiple Ca(2+) pathways in pulmonary arterial smooth muscle...
7.
Lin A, Leung G, Leung S, Vanhoutte P, Man R
Pharmacol Res . 2010 Nov; 63(3):181-9. PMID: 21111822
Genistein, a phytoestrogen present in soybeans, has well established vasodilator properties. The present study examined the mechanisms involved in the rapid vascular effects of genistein. Endothelium-dependent relaxations and contractions, induced...