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Amanda Chan

Explore the profile of Amanda Chan including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 573
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Recent Articles
1.
Cruz F, Cruz F, Orellano L, Chan A, Rock K
Cancer Immunol Res . 2024 Nov; 13(1):98-108. PMID: 39485834
MHC I antigen presentation allows CD8+ T cells to detect and eliminate cancerous or virally infected cells. The MHC I pathway is not essential for cell growth and viability, so...
2.
Girard A, Vimonpatranon S, Chan A, Jiang A, Huang D, Virtaneva K, et al.
Mucosal Immunol . 2024 May; 17(4):700-712. PMID: 38729611
Resident memory T cells (Ts) help control local immune homeostasis and contribute to tissue-protective immune responses. The local cues that guide their differentiation and localization are poorly defined. We demonstrate...
3.
Vimonpatranon S, Goes L, Chan A, Licavoli I, McMurry J, Wertz S, et al.
PLoS Pathog . 2023 Mar; 19(3):e1011209. PMID: 36897929
CD4+ tissue resident memory T cells (TRMs) are implicated in the formation of persistent HIV reservoirs that are established during the very early stages of infection. The tissue-specific factors that...
4.
Cruz F, Chan A, Rock K
Semin Immunol . 2023 Feb; 66:101729. PMID: 36804685
Phagocytes, particularly dendritic cells (DCs), generate peptide-major histocompatibility complex (MHC) I complexes from antigens they have collected from cells in tissues and report this information to CD8 T cells in...
5.
Kimonis E, Le B, Fleming G, Kyranides M, Demetriou C, Fanti K, et al.
J Child Psychol Psychiatry . 2022 Sep; 64(3):357-366. PMID: 36124731
Background: Elevated levels of callous-unemotional (CU) traits have proven useful for identifying a distinct subgroup of children whose conduct problems (CP) are early emerging, severe, persistent, and underpinned by aberrant...
6.
Young C, Kwan A, Yepez L, McCarty M, Chan A, Hsu D, et al.
BMC Cardiovasc Disord . 2021 Jul; 21(1):319. PMID: 34193076
Background: Since the early descriptions of large series of accessory atrioventricular pathway ablations in adults and adolescents over 20 years ago, there have been limited published reports based on more...
7.
Liang T, Wen D, Chen G, Chan A, Chen Z, Li H, et al.
Adv Mater . 2021 May; 33(26):e2100629. PMID: 33987883
Engineering of efficient and safe materials remains a challenge for cancer therapy. Here, the lipid droplet, an organelle in adipocytes, is demonstrated to be a controllable and biocompatible vehicle to...
8.
Shukla S, Chan A, Parvathaneni V, Gupta V
Int J Biol Macromol . 2020 May; 160:128-141. PMID: 32445818
The purpose of this study was to design and evaluate chitosan dispersed lipid vesicles (chitosomes) as potential delivery carriers for repurposing metformin (Met) against malignant pleural mesothelioma. Chitosomes were prepared...
9.
Abdou P, Wang Z, Chen Q, Chan A, Zhou D, Gunadhi V, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol . 2020 Apr; 12(5):e1632. PMID: 32255276
Cancer immunotherapy aims to leverage the immune system to suppress the growth of tumors and to inhibit metastasis. The recent promising clinical outcomes associated with cancer immunotherapy have prompted research...
10.
Chan A, Dziedziech A, Kirkman L, Deitsch K, Ankarklev J
Antimicrob Agents Chemother . 2020 Mar; 64(6). PMID: 32179524
Malaria parasites invade and replicate within red blood cells (RBCs), extensively modifying their structure and gaining access to the extracellular environment by placing the plasmodial surface anion channel (PSAC) into...