Amand F Schmidt
Overview
Explore the profile of Amand F Schmidt including associated specialties, affiliations and a list of published articles.
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57
Citations
1649
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Recent Articles
1.
Dziopa K, Chaturvedi N, Asselbergs F, Schmidt A
Commun Med (Lond)
. 2025 Mar;
5(1):77.
PMID: 40082712
Background: Cardiovascular disease (CVD) prediction models perform poorly in people with type 2 diabetes (T2DM). We aimed to identify potentially non-traditional CVD predictors for six facets of CVD (including coronary...
2.
Schmidt A, Davidson M, Ditmarsch M, Kastelein J, Finan C
Alzheimers Res Ther
. 2024 Dec;
16(1):276.
PMID: 39731193
No abstract available.
3.
Hassanzada F, Jansen M, van Lint F, Bosman L, Schmidt A, Dooijes D, et al.
Circ Genom Precis Med
. 2024 Dec;
17(6):e004561.
PMID: 39689185
Background: founder variants cause hypertrophic cardiomyopathy leading to heart failure and malignant ventricular arrhythmias. Exercise is typically regarded as a risk factor for disease expression although evidence is conflicting. Stratifying...
4.
Jurgens S, Ramo J, Kramarenko D, Wijdeveld L, Haas J, Chaffin M, et al.
Nat Genet
. 2024 Dec;
56(12):2843.
PMID: 39633063
No abstract available.
5.
Jurgens S, Ramo J, Kramarenko D, Wijdeveld L, Haas J, Chaffin M, et al.
Nat Genet
. 2024 Nov;
56(12):2636-2645.
PMID: 39572784
Dilated cardiomyopathy (DCM) is a heart muscle disease that represents an important cause of morbidity and mortality, yet causal mechanisms remain largely elusive. Here, we perform a large-scale genome-wide association...
6.
Molenaar M, Selder J, Schmidt A, Asselbergs F, Nieuwendijk J, van Dalfsen B, et al.
Eur Heart J Digit Health
. 2024 Nov;
5(6):702-711.
PMID: 39563909
Aims: This study aimed to validate the machine learning-based Global Registry of Acute Coronary Events (GRACE) 3.0 score and PRAISE (Prediction of Adverse Events following an Acute Coronary Syndrome) in...
7.
Schmidt A, Davidson M, Ditmarsch M, Kastelein J, Finan C
Alzheimers Res Ther
. 2024 Oct;
16(1):228.
PMID: 39415269
Background: Elevated concentrations of low-density lipoprotein cholesterol (LDL-C) are linked to dementia risk, and conversely, increased plasma concentrations of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein-A1 (Apo-A1) associate with decreased dementia...
8.
Gordillo-Maranon M, Schmidt A, Warwick A, Tomlinson C, Ytsma C, Engmann J, et al.
Commun Med (Lond)
. 2024 Oct;
4(1):195.
PMID: 39379679
Background: Despite the growing interest in the use of human genomic data for drug target identification and validation, the extent to which the spectrum of human disease has been addressed...
9.
Gratton J, Futema M, Humphries S, Hingorani A, Finan C, Schmidt A
JACC Adv
. 2024 Jun;
2(4):100333.
PMID: 38938233
Background: People with monogenic familial hypercholesterolemia (FH) are at an increased risk of premature coronary heart disease and death. With a prevalence of 1:250, FH is relatively common; but currently...
10.
Comparing the effects of CETP in East Asian and European ancestries: a Mendelian randomization study
Dunca D, Chopade S, Gordillo-Maranon M, Hingorani A, Kuchenbaecker K, Finan C, et al.
Nat Commun
. 2024 Jun;
15(1):5302.
PMID: 38906890
CETP inhibitors are a class of lipid-lowering drugs in development for treatment of coronary heart disease (CHD). Genetic studies in East Asian ancestry have interpreted the lack of CETP signal...