Amal Hofni
Overview
Explore the profile of Amal Hofni including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
39
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Recent Articles
1.
Mourad M, Mourad A, Elmaaty A, Hofni A, Khodir A, Aboubakr E, et al.
Bioorg Chem
. 2025 Mar;
157:108285.
PMID: 40043386
Wnt pathway is vital for survival of cancer-initiating cells. β-catenin plays a crucial role in Wnt pathway through interaction with TCF-4 to transcribe oncogenes. β-catenin activation suppresses immune cell infiltration...
2.
Hareeri R, Hofni A
Int Immunopharmacol
. 2024 Aug;
141:112931.
PMID: 39146781
Uterine inflammation affects 8% of women in the United States and 32% in developing nations, often caused by uncontrolled inflammation and oxidative stress. This condition significantly impacts women's health, productivity,...
3.
Mourad M, Elmaaty A, Zaki I, Mourad A, Hofni A, Khodir A, et al.
J Enzyme Inhib Med Chem
. 2023 May;
38(1):2205043.
PMID: 37165800
Topoisomerases II are ubiquitous enzymes with significant genotoxic effects in many critical DNA processes. Additionally, epidermal growth factor receptor (EGFR) plays pivotal role in tumour growth and angiogenesis. A novel...
4.
Hassan A, Hofni A, Abourehab M, Abdel-Rahman I
Int J Nanomedicine
. 2023 Mar;
18:1259-1280.
PMID: 36945254
Introduction: Ginger extract (GE) has sparked great interest due to its numerous biological benefits. However, it suffers from limited skin permeability, which challenges its transdermal application. The target of the...
5.
Hofni A, Ali F, Ibrahim A, Aboubaker E
Curr Mol Pharmacol
. 2023 Jan;
16(8):905-914.
PMID: 36698232
Objective: Diabetic nephropathy is an unavoidable complication of chronic uncontrolled diabetes mellitus. The pathogenesis of diabetic nephropathy is multifactorial, and the development of an effective therapy remains to be elucidated....
6.
Aboubakr E, Ibrahim A, Ali F, Mourad A, Ahmad A, Hofni A
Pharmaceuticals (Basel)
. 2022 Nov;
15(11).
PMID: 36422565
Methotrexate (MTX) is one of the most widely used cytotoxic chemotherapeutic agents, and it is used in the treatment of different autoimmune disorders. However, the clinical applications of MTX are...
7.
Samuel G, Nazim U, Sharma A, Manuel V, Elnaggar M, Taye A, et al.
J Pharm Sci
. 2021 Dec;
111(4):1197-1207.
PMID: 34929154
The main objective of this project was to formulate novel decorated amphiphilic PLGA nanoparticles aiming for the selective delivery of the novel peptide (CK-10) to the cancerous/tumor tissue. Novel modified...
8.
Hofni A, Shehata Messiha B, Mangoura S
Naunyn Schmiedebergs Arch Pharmacol
. 2017 May;
390(8):801-811.
PMID: 28493050
Endothelial dysfunction is a major contributor to the pathogenesis of vascular disease in diabetes mellitus and RhoA/Rho-kinase (ROCK) system appears to play a crucial role in this setting. The present...
9.
Hofni A, El-Moselhy M, Taye A, Khalifa M
Eur J Pharmacol
. 2014 Dec;
744:173-82.
PMID: 25446917
Diabetic nephropathy is one of the most common causes of end-stage kidney disease. Aldosterone and angiotensin II appear to play a crucial role in the pathogenesis of this disease. The...