Amaia Otxoa-de-Amezaga
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Explore the profile of Amaia Otxoa-de-Amezaga including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
322
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Recent Articles
1.
Martinez A, Heriche J, Calvo M, Tischer C, Otxoa-de-Amezaga A, Pedragosa J, et al.
Open Biol
. 2023 Jan;
13(1):220200.
PMID: 36629019
Microglia are very sensitive to changes in the environment and respond through morphological, functional and metabolic adaptations. To depict the modifications microglia undergo under healthy and pathological conditions, we developed...
2.
Palma A, Chara J, Montilla A, Otxoa-de-Amezaga A, Ruiz-Jaen F, Planas A, et al.
Front Cell Dev Biol
. 2022 Apr;
10:841548.
PMID: 35372341
Abnormalities in myelination are associated to behavioral and cognitive dysfunction in neurodevelopmental psychiatric disorders. Thus, therapies to promote or accelerate myelination could potentially ameliorate symptoms in autism. Clemastine, a histamine...
3.
Gallizioli M, Miro-Mur F, Otxoa-de-Amezaga A, Cugota R, Salas-Perdomo A, Justicia C, et al.
Cell Rep
. 2020 Oct;
33(3):108291.
PMID: 33086061
Brain CD11c cells share features with microglia and dendritic cells (DCs). Sterile inflammation increases brain CD11c cells, but their phenotype, origin, and functions remain largely unknown. We report that, after...
4.
Pedragosa J, Miro-Mur F, Otxoa-de-Amezaga A, Justicia C, Ruiz-Jaen F, Ponsaerts P, et al.
J Cereb Blood Flow Metab
. 2020 Mar;
40(1_suppl):S98-S116.
PMID: 32151226
Inflammatory Ly6CCCR2 monocytes infiltrate the brain after stroke but their functions are not entirely clear. We report that CCR2 monocytes and CCR2 lymphocytes infiltrate the brain after permanent ischemia. To...
5.
Otxoa-de-Amezaga A, Gallizioli M, Pedragosa J, Justicia C, Miro-Mur F, Salas-Perdomo A, et al.
Stroke
. 2019 May;
50(6):1548-1557.
PMID: 31084324
Background and Purpose- Ischemia attracts neutrophils to the injured brain. However, neutrophil location and access to the damaged brain tissue is not yet entirely understood. We aimed to investigate neutrophil...
6.
Brait V, Miro-Mur F, Perez-de-Puig I, Notario L, Hurtado B, Pedragosa J, et al.
Circ Res
. 2018 Dec;
124(2):279-291.
PMID: 30582456
Rationale: CD69 is an immunomodulatory molecule induced during lymphocyte activation. Following stroke, T-lymphocytes upregulate CD69 but its function is unknown. Objective: We investigated whether CD69 was involved in brain damage...
7.
Otxoa-de-Amezaga A, Miro-Mur F, Pedragosa J, Gallizioli M, Justicia C, Gaja-Capdevila N, et al.
Acta Neuropathol
. 2018 Dec;
137(2):321-341.
PMID: 30580383
Stroke attracts neutrophils to the injured brain tissue where they can damage the integrity of the blood-brain barrier and exacerbate the lesion. However, the mechanisms involved in neutrophil transmigration, location...
8.
Bonfill-Teixidor E, Otxoa-de-Amezaga A, Font-Nieves M, Sans-Fons M, Planas A
J Neuroinflammation
. 2017 Jan;
14(1):3.
PMID: 28086956
Background: Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E (PGE) is one of the products of COX activity. PGE has pleiotropic actions depending on the activation of specific...