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Alyne Almeida de Lima

Explore the profile of Alyne Almeida de Lima including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Opretzka L, Pinto C, Santos J, de Lima A, Soares M, Villarreal C
Biotechnol Lett . 2024 Jun; 46(5):907-924. PMID: 38900338
Mesenchymal stem/stromal cells (MSC) play a pivotal role in regenerative therapies. Recent studies show that factors secreted by MSC can replicate their biological activity, driving the emergence of cell-free therapy,...
2.
Opretzka L, Viana M, de Lima A, de Souza T, Scotti M, Tavares J, et al.
Pharmaceuticals (Basel) . 2023 Nov; 16(11). PMID: 38004413
Cleomin, a 1,3-oxazolidine-2-thione, was recently isolated from , a species traditionally used for treating painful conditions. Reports about the pharmacological activities of cleomin are lacking. Here, the antinociceptive effects of...
3.
do Espirito-Santo R, Santos D, Lauria P, de Lima A, Abreu L, Tavares J, et al.
J Nat Prod . 2023 Nov; 86(11):2514-2521. PMID: 37948340
Tonantzitlolone B (TZL-B) is a diterpene isolated from the roots of . Its antinociceptive effects were investigated in male Swiss mice using the following models of pain: formalin test, inflammation...
4.
Viana M, Lauria P, de Lima A, Opretzka L, Marcelino H, Villarreal C
Antioxidants (Basel) . 2022 Dec; 11(12). PMID: 36552628
Neuropathic pain (NP) is the most prevalent and debilitating form of chronic pain, caused by injuries or diseases of the somatosensory system. Since current first-line treatments only provide poor symptomatic...
5.
Viana M, de Lima A, Neto G, da Silva S, Leite A, Dos Santos E, et al.
Inflammation . 2021 Oct; 45(2):528-543. PMID: 34697722
Pain and inflammatory disorders are significant health problems because of prevalence and associated disabilities. In this context, LASSBio-596 is a hybrid compound able to modulate TNF-α and phosphodiesterases 4 and...
6.
de Farias Silva D, Simoes Bezerra P, Lopes de Sousa Ribeiro L, Viana M, de Lima A, Neto G, et al.
J Ethnopharmacol . 2020 Nov; 268:113607. PMID: 33242625
Ethnopharmacological Relevance: Since drugs currently used to manage pain and inflammatory conditions present several side effects, the investigation of new anti-inflammatory and antinociceptive agents from folk-medicine plants is an important...