Alvin S T Lim
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Explore the profile of Alvin S T Lim including associated specialties, affiliations and a list of published articles.
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10
Citations
348
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Recent Articles
1.
Tan A, Seet A, Lai G, Lim T, Lim A, Tan G, et al.
J Thorac Oncol
. 2020 Sep;
15(12):1928-1934.
PMID: 32866654
Introduction: RET rearrangements are an emerging targetable oncogenic fusion driver in NSCLC. However, the natural history of disease and activity of different classes of systemic therapy remain to be defined....
2.
Tan A, Lai G, Tan G, Poon S, Doble B, Lim T, et al.
Lung Cancer
. 2019 Dec;
139:207-215.
PMID: 31835042
Objectives: There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling traditional single biomarker...
3.
Lai G, Lim T, Lim J, Liew P, Kwang X, Nahar R, et al.
J Clin Oncol
. 2019 Jan;
37(11):876-884.
PMID: 30676858
Purpose: Mesenchymal epithelial transition factor ( MET) activation has been implicated as an oncogenic driver in epidermal growth factor receptor ( EGFR)-mutant non-small-cell lung cancer (NSCLC) and can mediate primary...
4.
Goh J, Feng M, Wang W, Oguz G, Yatim S, Lee P, et al.
Nat Med
. 2017 Oct;
23(11):1319-1330.
PMID: 28967919
Tumor recurrence remains the main reason for breast cancer-associated mortality, and there are unmet clinical demands for the discovery of new biomarkers and development of treatment solutions to benefit patients...
5.
Wong M, Ng C, Kuick C, Aw S, Rajasegaran V, Lim J, et al.
Histopathology
. 2017 Aug;
72(2):320-329.
PMID: 28833375
Aims: Clear cell sarcoma of the kidney (CCSK) is a rare paediatric renal malignant tumour. The majority of CCSKs have internal tandem duplications (ITDs) of the BCOR gene, whereas a...
6.
Lim A, Lim T
Methods Mol Biol
. 2016 Dec;
1541:119-125.
PMID: 27910019
Formalin-fixed paraffin-embedded (FFPE) tissues are typically the specimens available for FISH analysis of solid tissues, particularly of tumor specimens. Occasionally, tissue cores constructed as tissue microarrays from several patients are...
7.
Lim A, Krishnan S, Lim T, See K, Ng Y, Tan Y, et al.
Indian J Hematol Blood Transfus
. 2014 Dec;
30(4):253-8.
PMID: 25435723
Much effort has been made to stratify multiple myeloma patients for targeted therapy. However, responses have been varied and improved patient stratifications are needed. Forty-five diagnostic samples from multiple myeloma...
8.
Khoo B, Warkiani M, Tan D, Bhagat A, Irwin D, Lau D, et al.
PLoS One
. 2014 Jul;
9(7):e99409.
PMID: 24999991
Background: Circulating tumor cells (CTCs) are cancer cells that can be isolated via liquid biopsy from blood and can be phenotypically and genetically characterized to provide critical information for guiding...
9.
Lim A, Chen T, Lim T, Tan M, Lau L, Lim P, et al.
Ann Acad Med Singap
. 2010 Oct;
39(9):696-9.
PMID: 20957305
Introduction: High workload volumes in a Cytogenetics laboratory can lead to long result turn-around times (TAT). This study aimed to improve laboratory efficiency by adopting Lean Management System initiatives to...
10.
Lim A, Lim T, Kee S, Chia P, Raman S, Eu E, et al.
Ann Acad Med Singap
. 2008 Aug;
37(7):594-7.
PMID: 18695774
Introduction: Holoprosencephaly (HPE) is an uncommon congenital failure of forebrain development. Although the aetiology is heterogeneous, chromosomal abnormalities or a monogenic defect are the major causes, accounting for about 40%...