Allison C Sharrow
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Explore the profile of Allison C Sharrow including associated specialties, affiliations and a list of published articles.
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18
Citations
614
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Recent Articles
1.
Buj R, Cole A, Danielson J, Xu J, Hurd D, Kishore A, et al.
bioRxiv
. 2025 Feb;
PMID: 39975044
Approximately 50% of cancers exhibit decreased expression ( ), which is linked to immune checkpoint blockade (ICB) resistance. While is traditionally recognized as a tumor suppressor and cell cycle regulator,...
2.
Panesso-Gomez S, Cole A, Wield A, Anyaeche V, Shah J, Jiang Q, et al.
bioRxiv
. 2024 Nov;
PMID: 39605642
Chemoresistance is a major driver of cancer deaths. One understudied mechanism of chemoresistance is quiescence. We used single cell culture to identify, retrieve, and RNA-Seq profile primary quiescent ovarian cancer...
3.
Sharrow A, Megill E, Chen A, Farooqi A, Tangudu N, Uboveja A, et al.
Mol Metab
. 2024 Sep;
89:102031.
PMID: 39304063
Quiescence is a reversible cell cycle exit traditionally thought to be associated with a metabolically inactive state. Recent work in muscle cells indicates that metabolic reprogramming is associated with quiescence....
4.
Sharrow A, Megill E, Chen A, Farooqi A, McGonigal S, Hempel N, et al.
bioRxiv
. 2024 Jul;
PMID: 39026889
Quiescence is a reversible cell cycle exit traditionally thought to be associated with a metabolically inactive state. Recent work in muscle cells indicates that metabolic reprogramming is associated with quiescence....
5.
Sharrow A, Ho M, Dua A, Buj R, Blenman K, Orsulic S, et al.
bioRxiv
. 2023 Jul;
PMID: 37503008
The persistence of ovarian cancer stem-like cells (OvCSCs) after chemotherapy resistance has been implicated in relapse. However, the ability of these relatively quiescent cells to produce the robust tumor regrowth...
6.
Zhang Z, Hu J, Ishihara M, Sharrow A, Flora K, He Y, et al.
Int J Mol Sci
. 2022 Mar;
23(6).
PMID: 35328425
M2 macrophages in the tumor microenvironment are important drivers of cancer metastasis. Exosomes play a critical role in the crosstalk between different cells by delivering microRNAs or other cargos. Whether...
7.
de Rutte J, Dimatteo R, Archang M, van Zee M, Koo D, Lee S, et al.
ACS Nano
. 2022 Mar;
16(5):7242-7257.
PMID: 35324146
Techniques to analyze and sort single cells based on functional outputs, such as secreted products, have the potential to transform our understanding of cellular biology as well as accelerate the...
8.
Sharrow A, Ishihara M, Hu J, Kim I, Wu L
J Vis Exp
. 2020 Feb;
(155).
PMID: 32065133
Mouse models are the benchmark tests for in vivo cancer studies. However, cost, time, and ethical considerations have led to calls for alternative in vivo cancer models. The chicken chorioallantoic...
9.
Hu J, Schokrpur S, Archang M, Hermann K, Sharrow A, Khanna P, et al.
Mol Ther Methods Clin Dev
. 2018 May;
9:203-210.
PMID: 29766028
The CRISPR-based technology has revolutionized genome editing in recent years. This technique allows for gene knockout and evaluation of function in cell lines in a manner that is far easier...
10.
Hu J, Guan W, Liu P, Dai J, Tang K, Xiao H, et al.
Stem Cell Reports
. 2017 Aug;
9(2):464-477.
PMID: 28793246
Renal cell carcinoma (RCC) is a deadly malignancy due to its tendency to metastasize and resistance to chemotherapy. Stem-like tumor cells often confer these aggressive behaviors. We discovered an endoglin...