Allan Chris M Ferreon
Overview
Explore the profile of Allan Chris M Ferreon including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
38
Citations
1203
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Tsoi P, Choi K, Leonard P, Sizovs A, Moosa M, MacKenzie K, et al.
Angew Chem Int Ed Engl
. 2017 Aug;
56(41):12590-12593.
PMID: 28833982
Transactivation response element (TAR) DNA-binding protein 43 (TDP-43) misfolding is implicated in several neurodegenerative diseases characterized by aggregated protein inclusions. Misfolding is believed to be mediated by both the N-...
22.
Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll S, et al.
Nat Commun
. 2017 Jul;
8:16087.
PMID: 28703127
Glutathione plays many important roles in biological processes; however, the dynamic changes of glutathione concentrations in living cells remain largely unknown. Here, we report a reversible reaction-based fluorescent probe-designated as...
23.
Moosa M, Ferreon A, Deniz A
Chemphyschem
. 2014 Oct;
16(1):90-4.
PMID: 25345588
Intrinsically disordered proteins (IDPs) are involved in diverse cellular functions. Many IDPs can interact with multiple binding partners, resulting in their folding into alternative ligand-specific functional structures. For such multi-structural...
24.
Ferreon A, Ferreon J, Wright P, Deniz A
Nature
. 2013 Jun;
498(7454):390-4.
PMID: 23783631
Allostery is an intrinsic property of many globular proteins and enzymes that is indispensable for cellular regulatory and feedback mechanisms. Recent theoretical and empirical observations indicate that allostery is also...
25.
Ferreon A, Moosa M, Gambin Y, Deniz A
Proc Natl Acad Sci U S A
. 2012 Jul;
109(44):17826-31.
PMID: 22826265
Protein structure and function depend on a close interplay between intrinsic folding energy landscapes and the chemistry of the protein environment. Osmolytes are small-molecule compounds that can act as chemical...
26.
Ferreon A, Deniz A
Methods Mol Biol
. 2012 Jul;
896:257-66.
PMID: 22821530
Structural studies of intrinsically disordered proteins (IDPs) entail unique experimental challenges due in part to the lack of well-defined three-dimensional structures exhibited by this class of proteins. Although IDPs can...
27.
Ferreon A, Deniz A
Biochim Biophys Acta
. 2011 Feb;
1814(8):1021-9.
PMID: 21303706
The protein folding reaction carries great significance for cellular function and hence continues to be the research focus of a large interdisciplinary protein science community. Single-molecule methods are providing new...
28.
Gambin Y, VanDelinder V, Ferreon A, Lemke E, Groisman A, Deniz A
Nat Methods
. 2011 Feb;
8(3):239-41.
PMID: 21297620
We combined rapid microfluidic mixing with single-molecule fluorescence resonance energy transfer to study the folding kinetics of the intrinsically disordered human protein α-synuclein. The time-resolution of 0.2 ms revealed initial...
29.
Lee C, Ferreon J, Ferreon A, Arai M, Wright P
Proc Natl Acad Sci U S A
. 2010 Oct;
107(45):19290-5.
PMID: 20962272
The transcriptional activity of p53 is regulated by a cascade of posttranslational modifications. Although acetylation of p53 by CREB-binding protein (CBP)/p300 is known to be indispensable for p53 activation, the...
30.
Ferreon A, Moran C, Gambin Y, Deniz A
Methods Enzymol
. 2010 Jun;
472:179-204.
PMID: 20580965
Intrinsically disordered proteins (IDPs) (also referred to as natively unfolded proteins) play critical roles in a variety of cellular processes such as transcription and translation and also are linked to...