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Alison Smigova

Explore the profile of Alison Smigova including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 258
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Recent Articles
1.
Chaney A, Bauer M, Bochicchio D, Smigova A, Kassiou M, Davies K, et al.
J Neurochem . 2017 Nov; 144(3):318-335. PMID: 29124761
There is increasing evidence linking neuroinflammation to many neurological disorders including Alzheimer's disease (AD); however, its exact contribution to disease manifestation and/or progression is poorly understood. Therefore, there is a...
2.
Boutin H, Murray K, Pradillo J, Maroy R, Smigova A, Gerhard A, et al.
Eur J Nucl Med Mol Imaging . 2014 Oct; 42(3):503-11. PMID: 25351507
Purpose: Neuroinflammation plays a critical role in various neuropathological conditions, and hence there is renewed interest in the translocator protein (TSPO) as a biomarker of microglial activation and macrophage infiltration...
3.
Kadirvel M, Fairclough M, Cawthorne C, Rowling E, Babur M, McMahon A, et al.
Bioorg Med Chem . 2013 Dec; 22(1):341-9. PMID: 24290974
The diethyl ester of [(18)F]ML-10 is a small molecule apoptotic PET probe for cancer studies. Here we report a novel multi-step synthesis of the diethyl ester of ML-10 in excellent...
4.
Cawthorne C, Burrows N, Gieling R, Morrow C, Forster D, Gregory J, et al.
Mol Cancer Ther . 2013 Feb; 12(5):819-28. PMID: 23427298
The phosphoinositide 3-kinase (PI3K) pathway is deregulated in a range of cancers, and several targeted inhibitors are entering the clinic. This study aimed to investigate whether the positron emission tomography...
5.
Boutin H, Prenant C, Maroy R, Galea J, Greenhalgh A, Smigova A, et al.
PLoS One . 2013 Feb; 8(2):e56441. PMID: 23418569
Purpose: Neuroinflammation is involved in several brain disorders and can be monitored through expression of the translocator protein 18 kDa (TSPO) on activated microglia. In recent years, several new PET...
6.
Drake C, Boutin H, Jones M, Denes A, McColl B, Selvarajah J, et al.
Brain Behav Immun . 2011 Mar; 25(6):1113-22. PMID: 21356305
Chronic systemic inflammatory conditions, such as atherosclerosis, diabetes and obesity are associated with increased risk of stroke, which suggests that systemic inflammation may contribute to the development of stroke in...