Alise Zagare
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Explore the profile of Alise Zagare including associated specialties, affiliations and a list of published articles.
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8
Citations
753
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Recent Articles
1.
Mommaerts K, Monzel A, Zagare A, Nickels S, Diederich N, Longhino L, et al.
Parkinsons Dis
. 2025 Feb;
2025:5149071.
PMID: 39958955
Parkinson's disease is an age-related progressive neurodegenerative disorder. A large majority of Parkinson's disease patients have an unknown etiology, which is classified as idiopathic Parkinson's disease. Generating disease models directly...
2.
Chemla A, Arena G, Sacripanti G, Barmpa K, Zagare A, Garcia P, et al.
Brain
. 2025 Feb;
PMID: 39913247
The complex and heterogeneous nature of Parkinson's disease (PD) is still not fully understood, however, increasing evidence supports mitochondrial impairment as a major driver of neurodegeneration. Miro1, a mitochondrial GTPase...
3.
Zagare A, Kurlovics J, Almeida C, Ferrante D, Frangenberg D, Vitali A, et al.
J Tissue Eng
. 2025 Jan;
16:20417314241295928.
PMID: 39882547
Growing evidence indicates that type 2 diabetes (T2D) is associated with an increased risk of developing Parkinson's disease (PD) through shared disease mechanisms. Studies show that insulin resistance, which is...
4.
Zagare A, Hemedan A, Almeida C, Frangenberg D, Gomez-Giro G, Antony P, et al.
Mov Disord
. 2024 Nov;
40(1):67-76.
PMID: 39499190
Background: Parkinson's disease (PD) is the second most common, and the fastest-growing neurodegenerative disorder with unclear etiology in most cases. Therefore, the identification of non-genetic risk factors for PD pathology...
5.
Rosety I, Zagare A, Saraiva C, Nickels S, Antony P, Almeida C, et al.
NPJ Parkinsons Dis
. 2023 Dec;
9(1):166.
PMID: 38110400
The mechanisms underlying Parkinson's disease (PD) etiology are only partially understood despite intensive research conducted in the field. Recent evidence suggests that early neurodevelopmental defects might play a role in...
6.
Zagare A, Preciat G, Nickels S, Luo X, Monzel A, Gomez-Giro G, et al.
Commun Biol
. 2023 Nov;
6(1):1179.
PMID: 37985891
The vast majority of Parkinson's disease cases are idiopathic. Unclear etiology and multifactorial nature complicate the comprehension of disease pathogenesis. Identification of early transcriptomic and metabolic alterations consistent across different...
7.
Zagare A, Barmpa K, Smajic S, Smits L, Grzyb K, Grunewald A, et al.
Am J Hum Genet
. 2022 Jan;
109(2):311-327.
PMID: 35077669
Human brain organoid models that recapitulate the physiology and complexity of the human brain have a great potential for in vitro disease modeling, in particular for neurodegenerative diseases, such as...
8.
Zagare A, Gobin M, Monzel A, Schwamborn J
STAR Protoc
. 2021 May;
2(2):100524.
PMID: 34027482
The lack of advanced models recapitulating the human brain complexity is still a major obstacle in brain development and neurological disease research. Here, we describe a robust protocol to derive...
9.
Monzel A, Hemmer K, Kaoma T, Smits L, Bolognin S, Lucarelli P, et al.
Parkinsonism Relat Disord
. 2020 Jun;
75:105-109.
PMID: 32534431
Introduction: Brain organoids are highly complex multi-cellular tissue proxies, which have recently risen as novel tools to study neurodegenerative diseases such as Parkinson's disease (PD). However, with increasing complexity of...
10.
Heirendt L, Arreckx S, Pfau T, Mendoza S, Richelle A, Heinken A, et al.
Nat Protoc
. 2019 Feb;
14(3):639-702.
PMID: 30787451
Constraint-based reconstruction and analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental molecular systems biology data and quantitative prediction of physicochemically and biochemically feasible phenotypic states. The...